Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CTSK | P43235 | 9/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | APP | P05067 | 1/20 | 0.33 |
| ▸ | CTSS | P25774 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14468523 | 0.85 | LMNA (0.41) | CYP2D6CTSKHDAC1HDAC2HDAC8 | |
| SCHEMBL11053349 | 0.84 | CYP2D6 (0.44) | CYP2D6CTSKHDAC3HDAC1HDAC2 | |
| SCHEMBL17344466 | 0.84 | TSHR (0.38) | CYP2D6CTSKHDAC3HDAC1HDAC2 | |
| SCHEMBL22110452 | 0.83 | CTSK (0.47) | CTSKCA1CA2CTSS | |
| SCHEMBL24499071 | 0.83 | CTSK (0.32) | CYP2D6CTSKHDAC3HDAC1HDAC2 | |
| SCHEMBL5992371 | 0.82 | MAPT (0.42) | CYP2D6HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL6183615 | 0.82 | CYP2D6 (0.36) | CYP2D6CTSKHDAC3HDAC1HDAC2 | |
| SCHEMBL27603782 | 0.82 | CYP2D6 (0.36) | CYP2D6CTSKHDAC3HDAC1HDAC2 | |
| SCHEMBL7411881 | 0.82 | CYP2D6 (0.36) | CYP2D6CTSKHDAC3HDAC1HDAC2 | |
| SCHEMBL27291946 | 0.82 | CYP2D6 (0.36) | CYP2D6CTSKHDAC3HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009070485-A1 | DERIVATIVES OF 6,7-DIHYDRO-5H-IMIDAZO[1,2-α]IMIDAZOLE-3- CARBOXYLIC ACID AMIDES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-06-04 | — | — | WO | disclosed |