Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | GABRP | O00591 | 2/20 | 0.42 |
| ▸ | GABRD | O14764 | 2/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.42 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.42 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.42 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.42 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.42 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.42 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.42 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.42 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.42 |
| ▸ | GABRE | P78334 | 2/20 | 0.42 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.42 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.42 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.42 |
| ▸ | GABRQ | Q9UN88 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23727482 | 0.87 | CYP2D6 (0.41) | MAPTGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL17344466 | 0.82 | TSHR (0.38) | CYP2D6MEN1KMT2AGAAHDAC3 | |
| SCHEMBL11053349 | 0.82 | CYP2D6 (0.44) | CYP2D6MEN1KMT2AGAAHDAC3 | |
| SCHEMBL13804167 | 0.82 | CYP2D6 (0.37) | CYP2D6MEN1KMT2AGAAHDAC3 | |
| SCHEMBL22110452 | 0.81 | CTSK (0.47) | MAPTTSHR | |
| SCHEMBL6183615 | 0.81 | CYP2D6 (0.36) | CYP2D6MEN1KMT2AGAAHDAC3 | |
| SCHEMBL27291946 | 0.81 | CYP2D6 (0.36) | CYP2D6MEN1KMT2AGAAHDAC3 | |
| SCHEMBL7411881 | 0.81 | CYP2D6 (0.36) | CYP2D6MEN1KMT2AGAAHDAC3 | |
| SCHEMBL27603782 | 0.81 | CYP2D6 (0.36) | CYP2D6MEN1KMT2AGAAHDAC3 | |
| SCHEMBL28043657 | 0.81 | CYP2D6 (0.36) | CYP2D6MEN1KMT2AGAAHDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0917462-B1 | CELL ADHESION INHIBITORS | BIOGEN IDEC INC (US) | 2006-09-13 | — | — | EP | disclosed |
| US-20060030553-A1 | Cell adhesion inhibitors | ZHENG ZHONGLI | 2006-02-09 | — | — | US | disclosed |
| US-6949534-B2 | Cell adhesion inhibitors | BIOGEN IDEC MA INC. (US) | 2005-09-27 | — | — | US | disclosed |
| US-20040053907-A1 | Cell adhesion inhibitors | BIOGEN, INC. A MASSACHUSETTS CORPORATION. | 2004-03-18 | — | — | US | disclosed |
| CN-1478472-A | Cell adhesion inhibitor | ¸ | 2004-03-03 | — | — | CN | disclosed |
| US-6686350-B1 | Cell adhesion inhibitors | BIOGEN, INC. | 2004-02-03 | — | — | US | disclosed |
| EP-1179529-A1 | NOVEL HYDROXAMIC ACID DERIVATIVES | Daiichi Fine Chemical Co., Ltd. (JP) | 2002-02-13 | — | — | EP | disclosed |
| CN-1230110-A | Cell adhesion inhibitors | BIOGEN INC (US) | 1999-09-29 | — | — | CN | disclosed |
| EP-0917462-A1 | CELL ADHESION INHIBITORS | BIOGEN, INC. (US) | 1999-05-26 | — | — | EP | disclosed |
| WO-1998004247-A1 | CELL ADHESION INHIBITORS | BIOGEN, INC. (US) | 1998-02-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040053907-A1 | Cell adhesion inhibitors | ICAM1, VCAM1, EPCAM | MAPT 2771/4885GABRP 3251/4885GABRD 3911/4885 |
| US-20060030553-A1 | Cell adhesion inhibitors | ICAM1, VCAM1, EPCAM | MAPT 2771/4885GABRP 3251/4885GABRD 3911/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.