Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VDR | P11473 | 7/20 | 0.59 |
| ▸ | CYP24A1 | Q07973 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13804812 | 1.00 | VDR (0.59) | VDRCYP24A1 | |
| SCHEMBL13993787 | 0.92 | VDR (0.59) | VDR | |
| SCHEMBL13993777 | 0.91 | VDR (0.58) | VDR | |
| SCHEMBL14356235 | 0.90 | VDR (0.63) | VDR | |
| SCHEMBL26322428 | 0.88 | VDR (0.68) | VDR | |
| SCHEMBL26322425 | 0.87 | VDR (0.59) | VDR | |
| SCHEMBL26324018 | 0.85 | VDR (0.57) | VDR | |
| SCHEMBL13804835 | 0.84 | VDR (0.52) | VDRCYP24A1 | |
| SCHEMBL13993785 | 0.84 | VDR (0.54) | VDR | |
| SCHEMBL26322277 | 0.83 | VDR (0.59) | VDRCYP24A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090143342-A1 | 26,27-homologated-20-EPI-2-alkylidene-19-nor-vitamin D compounds | WISCONSIN ALUMNI RESEARCH FOUNDATION OF MADISON | 2009-06-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090143342-A1 | 26,27-homologated-20-EPI-2-alkylidene-19-nor-vitamin D compounds | VDR, CYP24A1, CYP2R1 | VDR 1/4885CYP24A1 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.