Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VDR | P11473 | 10/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13804812 | 0.91 | VDR (0.59) | VDR | |
| SCHEMBL13993787 | 0.91 | VDR (0.59) | VDR | |
| SCHEMBL13804827 | 0.91 | VDR (0.59) | VDR | |
| SCHEMBL14356235 | 0.90 | VDR (0.63) | VDR | |
| SCHEMBL26322428 | 0.87 | VDR (0.68) | VDR | |
| SCHEMBL26322425 | 0.86 | VDR (0.59) | VDR | |
| SCHEMBL26324018 | 0.85 | VDR (0.57) | VDR | |
| SCHEMBL13993785 | 0.83 | VDR (0.54) | VDR | |
| SCHEMBL5069262 | 0.82 | VDR (0.52) | VDR | |
| SCHEMBL22679443 | 0.82 | VDR (0.52) | VDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7468361-B2 | 2-ethyl and 2-ethylidene-19-nor-vitamin D compounds | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2008-12-23 | — | — | US | disclosed |
| US-20080032956-A1 | 2-Ethyl and 2-Ethylidene-19-Nor-Vitamin D Compounds | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2008-02-07 | — | — | US | disclosed |
| US-7300925-B2 | 2-ethyl and 2-ethylidene-19-nor-vitamin D compounds | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2007-11-27 | — | — | US | disclosed |
| US-20070088008-A1 | 2-Ethyl and 2-ethylidene-19-nor-vitamin D compounds | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2007-04-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080032956-A1 | 2-Ethyl and 2-Ethylidene-19-Nor-Vitamin D Compounds | CYP24A1, VDR, CYP2R1 | VDR 2/4885 |
| US-20070088008-A1 | 2-Ethyl and 2-ethylidene-19-nor-vitamin D compounds | CYP24A1, VDR, CYP2R1 | VDR 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.