Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | TP53 | P04637 | 3/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 2/20 | 0.34 |
| ▸ | ACHE | P22303 | 5/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | THRA | P10827 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | ESR1 | P03372 | 1/20 | 0.30 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.30 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15682853 | 0.74 | TP53 (0.42) | MAPTTP53RXFP1THRBSMN1; SMN2 | |
| SCHEMBL3989474 | 0.73 | ALDH1A1 (0.52) | MAPTTP53RXFP1SMN1; SMN2LMNA | |
| SCHEMBL3998870 | 0.66 | ALDH1A1 (0.54) | MAPTTP53RXFP1LMNAALDH1A1 | |
| SCHEMBL15948520 | 0.60 | ALDH1A1 (0.39) | MAPTTP53RXFP1THRBSMN1; SMN2 | |
| SCHEMBL5141996 | 0.59 | ALDH1A1 (0.44) | SMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL7039240 | 0.58 | ALDH1A1 (0.38) | MAPTTP53RXFP1SMN1; SMN2ALDH1A1 | |
| SCHEMBL12312177 | 0.58 | CES2 (0.41) | MAPTTP53RXFP1THRBALDH1A1 | |
| SCHEMBL11986379 | 0.57 | PPARG (0.46) | TP53THRBTHRA | |
| SCHEMBL4146764 | 0.57 | ALDH1A1 (0.46) | SMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL948161 | 0.57 | ALDH1A1 (0.46) | SMN1; SMN2ALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009069966-A2 | USE OF COMPOUNDS FOR CONTROLLING THE FUNCTION OF SPHINGOSYLPHOSPHORYLCHOLINE | AMOREPACIFIC CORPORATION (KR) | 2009-06-04 | — | — | WO | disclosed |