Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KISS1R | Q969F8 | 5/20 | 0.39 |
| ▸ | ACE | P12821 | 1/20 | 0.39 |
| ▸ | NPY4R | P50391 | 8/20 | 0.39 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.37 |
| ▸ | NPY1R | P25929 | 5/20 | 0.36 |
| ▸ | CTSL | P07711 | 1/20 | 0.36 |
| ▸ | CTSS | P25774 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 1/20 | 0.36 |
| ▸ | NPY2R | P49146 | 3/20 | 0.36 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13805250 | 0.95 | KISS1R (0.41) | KISS1RNPY4RNPY1RNPY2RNPY5R | |
| SCHEMBL13804935 | 0.90 | ANPEP (0.44) | KISS1RNPY4RNPY1RALDH1A1LMNA | |
| SCHEMBL13804931 | 0.85 | ANPEP (0.44) | KISS1RNPY4RNPY1RNPY2RNPY5R | |
| Trifluoroacetic Acid SCHEMBL8114483 | 0.76 | CHIT1 (0.38) | KLKB1NPY1R | |
| SCHEMBL8120727 | 0.75 | F2 (0.39) | NPY4RNPY1R | |
| SCHEMBL8119098 | 0.74 | NPC1 (0.38) | KLKB1ALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL8111954 | 0.73 | F2 (0.35) | KISS1RNPY4RNPY1RLMNA | |
| SCHEMBL8119391 | 0.71 | NPY1R (0.43) | NPY4RNPY1RNPY2RNPY5R | |
| SCHEMBL8114868 | 0.71 | MC4R (0.37) | KISS1RNPY1R | |
| SCHEMBL8119124 | 0.71 | F2 (0.36) | KISS1RNPY1REPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1524962-B1 | COMPOSITIONS AND METHODS FOR DARKENING THE SKIN | JOHNSON & JOHNSON CONSUMER (US) | 2009-06-03 | — | — | EP | disclosed |