Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 1/20 | 0.44 |
| ▸ | KISS1R | Q969F8 | 4/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | MMP1 | P03956 | 2/20 | 0.40 |
| ▸ | MMP3 | P08254 | 1/20 | 0.40 |
| ▸ | FNTA | P49354 | 1/20 | 0.40 |
| ▸ | FNTB | P49356 | 1/20 | 0.40 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.40 |
| ▸ | BMP1 | P13497 | 3/20 | 0.40 |
| ▸ | NPY4R | P50391 | 2/20 | 0.39 |
| ▸ | NPY1R | P25929 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13804931 | 0.95 | ANPEP (0.44) | ANPEPKISS1RMMP1MMP3NPY4R | |
| SCHEMBL13804934 | 0.90 | KISS1R (0.39) | KISS1RNPY4RNPY1RALDH1A1LMNA | |
| SCHEMBL13805250 | 0.85 | KISS1R (0.41) | KISS1RNPY4RNPY1R | |
| SCHEMBL8119098 | 0.77 | NPC1 (0.38) | ALDH1A1 | |
| SCHEMBL8122121 | 0.76 | HDAC1 (0.48) | BMP1NPY1RALDH1A1 | |
| SCHEMBL7037362 | 0.76 | NPY1R (0.50) | NPY4RNPY1RGAA | |
| SCHEMBL8119391 | 0.74 | NPY1R (0.43) | NPY4RNPY1R | |
| SCHEMBL8114868 | 0.74 | MC4R (0.37) | KISS1RNPY1R | |
| SCHEMBL24446771 | 0.74 | ANPEP (0.59) | ANPEPATMMMP1MMP3ALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL8114483 | 0.73 | CHIT1 (0.38) | NPY1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1524962-B1 | COMPOSITIONS AND METHODS FOR DARKENING THE SKIN | JOHNSON & JOHNSON CONSUMER (US) | 2009-06-03 | — | — | EP | disclosed |