SCHEMBL13805694

SCHEMBL13805694

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nearest known ligand 0.32

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ C3AR1 Q16581 1/20 0.32
▸ POLB P06746 1/20 0.31
▸ HSD17B10 Q99714 1/20 0.31
▸ ALB P02768 1/20 0.31
▸ FURIN P09958 3/20 0.31
▸ NPY1R P25929 2/20 0.31
▸ NPY4R P50391 2/20 0.31
▸ IL23R Q5VWK5 1/20 0.30
▸ OPRK1 P41145 2/20 0.30
▸ FAP Q12884 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17722918 0.93 GLP1R (0.33) C3AR1NPY1RNPY4ROPRK1FAP
SCHEMBL13805702 0.93 FURIN (0.32) C3AR1POLBHSD17B10FURINNPY1R
SCHEMBL13311280 0.91 POLB (0.33) POLBHSD17B10
SCHEMBL13310984 0.88 FAP (0.36) FURINNPY1RNPY4ROPRK1FAP
SCHEMBL17841870 0.87 GLP1R (0.40) C3AR1POLBFURINNPY1RFAP
SCHEMBL20263703 0.87 GLP1R (0.40) C3AR1POLBFURINNPY1RFAP
SCHEMBL20263702 0.87 GLP1R (0.40) C3AR1POLBFURINNPY1RFAP
SCHEMBL22841031 0.87 GLP1R (0.33) C3AR1POLBHSD17B10NPY1RNPY4R
SCHEMBL22115954 0.87 GLP1R (0.40) C3AR1POLBFURINNPY1RFAP
SCHEMBL17842470 0.87 GLP1R (0.40) C3AR1POLBFURINNPY1RFAP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090162372-A1 FIBRONECTIN ED-B ANTIBODIES, CONJUGATES THEREOF, AND METHODS OF USE MEDAREX, INC. (US) 2009-06-25 — — US disclosed
US-20090162372-A1 FIBRONECTIN ED-B ANTIBODIES, CONJUGATES THEREOF, AND METHODS OF USE MEDAREX, INC. (US) 2009-06-25 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090162372-A1 FIBRONECTIN ED-B ANTIBODIES, CONJUGATES THEREOF, AND METHODS OF USE FN1, EDNRB, EDF1 C3AR1 153/4885POLB 3600/4885HSD17B10 4045/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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