SCHEMBL17722918

SCHEMBL17722918

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nearest known ligand 0.33

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ GLP1R P43220 9/20 0.33
▸ FAP Q12884 3/20 0.33
▸ OPRK1 P41145 2/20 0.32
▸ C3AR1 Q16581 1/20 0.32
▸ RXFP1 Q9HBX9 1/20 0.32
▸ HRH1 P35367 2/20 0.32
▸ NPY1R P25929 1/20 0.32
▸ NPY4R P50391 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13805694 0.93 C3AR1 (0.32) FAPOPRK1C3AR1NPY1RNPY4R
SCHEMBL31395485 0.93 GLP1R (0.40) GLP1RFAPC3AR1NPY1R
SCHEMBL17842470 0.93 GLP1R (0.40) GLP1RFAPC3AR1NPY1R
SCHEMBL19777071 0.93 GLP1R (0.40) GLP1RFAPC3AR1NPY1R
SCHEMBL20263703 0.93 GLP1R (0.40) GLP1RFAPC3AR1NPY1R
SCHEMBL17841870 0.93 GLP1R (0.40) GLP1RFAPC3AR1NPY1R
SCHEMBL19776684 0.93 GLP1R (0.40) GLP1RFAPC3AR1NPY1R
SCHEMBL22841031 0.93 GLP1R (0.33) GLP1RFAPC3AR1HRH1NPY1R
SCHEMBL22115954 0.93 GLP1R (0.40) GLP1RFAPC3AR1NPY1R
SCHEMBL20263702 0.93 GLP1R (0.40) GLP1RFAPC3AR1NPY1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230321271-A1 ANTI-cMet ANTIBODY DRUG CONJUGATES AND METHODS FOR THEIR USE ABBVIE BIOTHERAPEUTICS INC. (US) 2023-10-12 — — US disclosed
EP-4233909-A2 ANTI-CMET ANTIBODY DRUG CONJUGATES AND METHODS FOR THEIR USE AbbVie Biotherapeutics Inc. (US) 2023-08-30 — — EP disclosed
EP-3804765-A1 ANTI-CMET ANTIBODY DRUG CONJUGATES AND METHODS FOR THEIR USE AbbVie Biotherapeutics Inc. (US) 2021-04-14 — — EP disclosed
WO-2020236792-A1 CD19 BINDING MOLECULES AND USES THEREOF NOVARTIS AG (CH) 2020-11-26 — — WO disclosed
EP-3383909-B1 ANTI-HUMAN LRRC15 ANTIBODY DRUG CONJUGATES AND METHODS FOR THEIR USE ABBVIE INC (US) 2020-06-17 — — EP disclosed
EP-3458102-B1 ANTI-CMET ANTIBODY DRUG CONJUGATES AND METHODS FOR THEIR USE ABBVIE BIOTHERAPEUTICS INC (US) 2020-06-17 — — EP disclosed
US-20170348429-A1 ANTI-cMET ANTIBODY DRUG CONJUGATES AND METHODS FOR THEIR USE AbbVie Manufacturing Management Unlimited Company (IE) 2017-12-07 — — US disclosed
WO-2017095805-A1 ANTI-huLRRC15 ANTIBODY DRUG CONJUGATES AND METHODS FOR THEIR USE ABBVIE INC. (US) 2017-06-08 — — WO disclosed
US-20170151343-A1 ANTI-huLRRC15 ANTIBODY DRUG CONJUGATES AND METHODS FOR THEIR USE ABBVIE INC. 2017-06-01 — — US disclosed
US-20170151344-A1 ANTI-huLRRC15 ANTIBODY DRUG CONJUGATES AND METHODS FOR THEIR USE ABBVIE INC. 2017-06-01 — — US disclosed
US-20160122430-A1 ANTI-CS1 ANTIBODIES AND ANTIBODY DRUG CONJUGATES ABBVIE BIOTHERAPEUTICS INC. 2016-05-05 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170151343-A1 ANTI-huLRRC15 ANTIBODY DRUG CONJUGATES AND METHODS FOR THEIR USE LRRC59, LRRC47, HACD3 GLP1R 2892/4885FAP 4569/4885OPRK1 3286/4885
US-20170151344-A1 ANTI-huLRRC15 ANTIBODY DRUG CONJUGATES AND METHODS FOR THEIR USE LRRC59, LRRC47, HACD3 GLP1R 2892/4885FAP 4569/4885OPRK1 3286/4885
US-20160122430-A1 ANTI-CS1 ANTIBODIES AND ANTIBODY DRUG CONJUGATES CD47, CSGALNACT1, CSE1L GLP1R 4715/4885FAP 4279/4885OPRK1 4782/4885
US-20170348429-A1 ANTI-cMET ANTIBODY DRUG CONJUGATES AND METHODS FOR THEIR USE MMAB, HNMT, SHMT1 GLP1R 3360/4885FAP 3032/4885OPRK1 3214/4885
US-20230321271-A1 ANTI-cMet ANTIBODY DRUG CONJUGATES AND METHODS FOR THEIR USE MMAB, HNMT, SHMT1 GLP1R 3360/4885FAP 3032/4885OPRK1 3214/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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