Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP1A | P62942 | 6/20 | 0.57 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.44 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.44 |
| ▸ | ITGAL | P20701 | 1/20 | 0.44 |
| ▸ | DPP3 | Q9NY33 | 4/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 4/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 4/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 4/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.43 |
| ▸ | HDAC9 | Q9UKV0 | 4/20 | 0.43 |
| ▸ | HDAC5 | Q9UQL6 | 4/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | DPP4 | P27487 | 1/20 | 0.42 |
| ▸ | KRAS | P01116 | 1/20 | 0.42 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8268308 | 0.90 | FKBP1A (0.55) | FKBP1AITGB2ICAM1ITGALDPP3 | |
| SCHEMBL630918 | 0.87 | FKBP1A (0.45) | FKBP1AITGB2ICAM1ITGALHDAC3 | |
| SCHEMBL1384829 | 0.85 | KMT2A (0.50) | FKBP1AITGB2ICAM1ITGALDPP3 | |
| SCHEMBL1383977 | 0.85 | KMT2A (0.50) | FKBP1AITGB2ICAM1ITGALDPP3 | |
| SCHEMBL1385938 | 0.79 | F2 (0.51) | MEN1LMNAMAPTKMT2A | |
| SCHEMBL1380411 | 0.79 | F2 (0.51) | MEN1LMNAMAPTKMT2A | |
| SCHEMBL1381877 | 0.78 | ITGB2 (0.42) | ITGB2ICAM1ITGALDPP3CYP2C19 | |
| SCHEMBL13206955 | 0.75 | ITGB2 (0.52) | ITGB2ICAM1ITGALDPP3MEN1 | |
| SCHEMBL631002 | 0.75 | ITGB2 (0.52) | ITGB2ICAM1ITGALDPP3MEN1 | |
| SCHEMBL629768 | 0.75 | ITGB2 (0.52) | ITGB2ICAM1ITGALDPP3MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4812758-B2 | — | — | 2011-11-09 | — | — | JP | claimed |