Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB2 | P05107 | 1/20 | 0.52 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.52 |
| ▸ | ITGAL | P20701 | 1/20 | 0.52 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.49 |
| ▸ | ITGA5 | P08648 | 2/20 | 0.49 |
| ▸ | F10 | P00742 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | DPP3 | Q9NY33 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13206955 | 1.00 | ITGB2 (0.52) | ITGB2ICAM1ITGALITGB1ITGA5 | |
| SCHEMBL629768 | 1.00 | ITGB2 (0.52) | ITGB2ICAM1ITGALITGB1ITGA5 | |
| SCHEMBL1383977 | 0.89 | KMT2A (0.50) | ITGB2ICAM1ITGALITGB1ITGA5 | |
| SCHEMBL1384829 | 0.89 | KMT2A (0.50) | ITGB2ICAM1ITGALITGB1ITGA5 | |
| SCHEMBL630229 | 0.89 | MMP9 (0.54) | ITGB2ICAM1ITGALITGB1ITGA5 | |
| SCHEMBL8268055 | 0.88 | ITGB2 (0.51) | ITGB2ICAM1ITGALKMT2AMEN1 | |
| SCHEMBL8268308 | 0.86 | FKBP1A (0.55) | ITGB2ICAM1ITGALF10DPP3 | |
| SCHEMBL13206992 | 0.85 | ITGB2 (0.46) | ITGB2ICAM1ITGALF10 | |
| SCHEMBL7069023 | 0.84 | ALOX5 (0.59) | ITGB2ICAM1ITGALITGB1ITGA5 | |
| SCHEMBL630426 | 0.84 | TDP1 (0.48) | ITGB2ICAM1ITGALKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1778637-B1 | FKBP-binding composition and pharmaceutical use thereof | AVENTIS PHARMA INC (US) | 2012-02-22 | — | — | EP | disclosed |
| EP-1778637-A2 | FKBP BINDING COMPOSITION AND PHARMACEUTICAL USE THEREOF | Aventis Pharmaceuticals, Inc. (US) | 2007-05-02 | — | — | EP | disclosed |
| WO-2006012256-A2 | FKBP BINDING COMPOSITION AND PHARMACEUTICAL USE THEREOF | AVENTIS PHARMACEUTICALS INC. (US) | 2006-02-02 | — | — | WO | disclosed |