Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | PKM | P14618 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | FKBP1A | P62942 | 2/20 | 0.48 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.47 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.47 |
| ▸ | ITGAL | P20701 | 1/20 | 0.47 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.47 |
| ▸ | ITGA5 | P08648 | 2/20 | 0.47 |
| ▸ | DPP3 | Q9NY33 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1383977 | 1.00 | KMT2A (0.50) | KMT2APKMMEN1ALDH1A1LMNA | |
| SCHEMBL1385938 | 0.90 | F2 (0.51) | KMT2AMEN1LMNAMAPTSMN1; SMN2 | |
| SCHEMBL1380411 | 0.90 | F2 (0.51) | KMT2AMEN1LMNAMAPTSMN1; SMN2 | |
| SCHEMBL629768 | 0.89 | ITGB2 (0.52) | KMT2APKMMEN1ALDH1A1LMNA | |
| SCHEMBL631002 | 0.89 | ITGB2 (0.52) | KMT2APKMMEN1ALDH1A1LMNA | |
| SCHEMBL13206955 | 0.89 | ITGB2 (0.52) | KMT2APKMMEN1ALDH1A1LMNA | |
| SCHEMBL631775 | 0.86 | LMNA (0.47) | KMT2APKMMEN1ALDH1A1LMNA | |
| SCHEMBL630426 | 0.85 | TDP1 (0.48) | KMT2APKMMEN1ALDH1A1LMNA | |
| SCHEMBL1380574 | 0.85 | FKBP1A (0.57) | KMT2AMEN1LMNAFKBP1AITGB2 | |
| SCHEMBL630229 | 0.85 | MMP9 (0.54) | KMT2APKMMEN1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4812758-B2 | — | — | 2011-11-09 | — | — | JP | claimed |