Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 16/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.46 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1381539 | 0.91 | F10 (0.59) | F10ALDH1A1KMT2APTGS2 | |
| SCHEMBL1379173 | 0.86 | F10 (0.57) | F10ALDH1A1KMT2A | |
| SCHEMBL1380646 | 0.84 | F10 (0.62) | F10PTGS2 | |
| SCHEMBL1383122 | 0.83 | F10 (0.60) | F10PTGS2P2RX4 | |
| SCHEMBL1382884 | 0.83 | F10 (0.55) | F10ALDH1A1 | |
| SCHEMBL6181035 | 0.82 | F10 (0.60) | F10ALDH1A1KMT2A | |
| SCHEMBL1379341 | 0.82 | F10 (0.55) | F10P2RX4 | |
| SCHEMBL1679321 | 0.82 | F10 (0.65) | F10PTGS2 | |
| SCHEMBL6179994 | 0.81 | F10 (0.59) | F10PTGS2 | |
| SCHEMBL1380603 | 0.81 | F10 (0.59) | F10ALDH1A1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004065369-A1 | CARBOXAMIDE DERIVATIVES AND THEIR USE AS FACTOR XA INHIBITORS | MERCK PATENT GMBH (DE) | 2004-08-05 | — | — | WO | disclosed |