Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDR1 | Q08345 | 2/20 | 0.59 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.55 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.54 |
| ▸ | KCNQ3 | O43525 | 2/20 | 0.54 |
| ▸ | KCNQ2 | O43526 | 2/20 | 0.54 |
| ▸ | KCNE1 | P15382 | 2/20 | 0.54 |
| ▸ | KCNQ1 | P51787 | 2/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.53 |
| ▸ | KCNQ5 | Q9NR82 | 1/20 | 0.53 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.53 |
| ▸ | CES2 | O00748 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30069240 | 0.88 | LMNA (0.73) | P2RX1LMNAPTGS1MAPTKCNK3 | |
| SCHEMBL30739967 | 0.85 | LMNA (0.78) | P2RX1LMNAPTGS1MAPTKCNK3 | |
| SCHEMBL20910377 | 0.79 | PTGS2 (0.58) | LMNAMAPTKCNK3KCNQ3KCNQ2 | |
| SCHEMBL28020270 | 0.79 | KCNK3 (0.65) | P2RX1LMNAMAPTKCNK3KAT6A | |
| SCHEMBL16672355 | 0.79 | NPY5R (0.45) | DDR1LMNAMAPTNPSR1MEN1 | |
| SCHEMBL4766873 | 0.79 | KCNK3 (0.72) | P2RX1LMNAPTGS1MAPTKCNK3 | |
| SCHEMBL27389992 | 0.78 | PTGS2 (0.75) | LMNAMAPTKCNK3MEN1KMT2A | |
| SCHEMBL16554416 | 0.77 | KCNQ3 (0.51) | DDR1MAPTKCNQ3KCNQ2KCNE1 | |
| SCHEMBL28971351 | 0.77 | TLR7 (0.63) | P2RX1LMNAPTGS1MAPTKCNK3 | |
| SCHEMBL11678493 | 0.76 | MEN1 (0.51) | LMNAMAPTNPSR1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009070533-A1 | METHODS OF INHIBITING STEROYL COA DESATURASE | COMPLEGEN, INC. (US) | 2009-06-04 | — | — | WO | disclosed |