Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.41 |
| ▸ | GCK | P35557 | 4/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 5/20 | 0.37 |
| ▸ | RAB9A | P51151 | 5/20 | 0.37 |
| ▸ | MITF | O75030 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.36 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.36 |
| ▸ | REN | P00797 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1378225 | 0.89 | KMT2A (0.42) | SMN1; SMN2LMNAKDM4EMAPK1MAPK10 | |
| SCHEMBL5478920 | 0.85 | LMNA (0.40) | LMNATP53MAPTMEN1KMT2A | |
| SCHEMBL4866640 | 0.85 | MAPT (0.41) | SMN1; SMN2LMNAKDM4ETP53MAPT | |
| SCHEMBL5483266 | 0.85 | MAPT (0.46) | SMN1; SMN2LMNAKDM4EMAPK1MAPK10 | |
| SCHEMBL5492474 | 0.84 | POLB (0.42) | SMN1; SMN2LMNAKDM4ETP53MAPT | |
| SCHEMBL4593955 | 0.80 | SSTR5 (0.39) | LMNAKDM4ETP53MAPTREN | |
| SCHEMBL5483270 | 0.80 | KMT2A (0.44) | SMN1; SMN2LMNAKDM4EMEN1KMT2A | |
| SCHEMBL5486670 | 0.80 | CETP (0.39) | SMN1; SMN2MAPTRAB9AMEN1KMT2A | |
| SCHEMBL4593502 | 0.79 | REN (0.39) | SMN1; SMN2LMNAKDM4ETP53MAPT | |
| SCHEMBL4594411 | 0.79 | REN (0.43) | TP53MAPTREN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4708474-B2 | — | — | 2011-06-22 | — | — | JP | claimed |