Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 5/20 | 0.31 |
| ▸ | CHRNB4 | P30926 | 5/20 | 0.31 |
| ▸ | CHRNA3 | P32297 | 5/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 5/20 | 0.31 |
| ▸ | CHRNA7 | P36544 | 4/20 | 0.30 |
| ▸ | CCR5 | P51681 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22699178 | 0.83 | — | — | |
| SCHEMBL18495100 | 0.83 | — | — | |
| SCHEMBL18013402 | 0.79 | — | — | |
| SCHEMBL66407 | 0.77 | — | — | |
| SCHEMBL29323802 | 0.76 | SIGMAR1 (0.35) | — | |
| SCHEMBL21038639 | 0.76 | CHKA (0.32) | — | |
| SCHEMBL18599846 | 0.74 | HTR6 (0.31) | — | |
| Ammonia Solution, Strong SCHEMBL27932780 | 0.74 | — | — | |
| SCHEMBL12579677 | 0.73 | CCR5 (0.43) | CCR5 | |
| SCHEMBL17057342 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009071638-A2 | PROCESS FOR THE PREPARATION OF 2-(PRIMARY/SECONDARY AMINO)HYDROCARBYL)- CARBAMOYL-7-OXO-2,6-DIAZA-BICYCLO[3.2.0.]HEPTANE-6-SULFONIC ACID DERIVATIVES | BASILEA PHARMACEUTICA AG (CH) | 2009-06-11 | — | — | WO | disclosed |