Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR4 | O95977 | 12/20 | 0.52 |
| ▸ | S1PR5 | Q9H228 | 3/20 | 0.52 |
| ▸ | HPGD | P15428 | 4/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | S1PR2 | O95136 | 5/20 | 0.45 |
| ▸ | S1PR3 | Q99500 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21119020 | 0.85 | MAPT (0.56) | S1PR4S1PR5HPGDHTTMAPT | |
| SCHEMBL19237535 | 0.82 | S1PR4 (0.47) | S1PR4S1PR5HPGDHTTMAPT | |
| SCHEMBL9970933 | 0.79 | ALDH1A1 (0.50) | S1PR4HPGDHTTMAPTNPSR1 | |
| SCHEMBL10028047 | 0.79 | HPGD (0.53) | S1PR4S1PR5HPGDHTTMAPT | |
| SCHEMBL13044123 | 0.76 | S1PR4 (0.60) | S1PR4S1PR5MAPTNPSR1TDP1 | |
| SCHEMBL805123 | 0.75 | HSD17B2 (0.52) | S1PR4S1PR5HPGDHTTMAPT | |
| SCHEMBL799579 | 0.75 | HPGD (0.49) | S1PR4S1PR5HPGDHTTMAPT | |
| SCHEMBL13809594 | 0.74 | MEN1 (0.54) | HPGDHTTMAPTNPSR1TDP1 | |
| SCHEMBL18539932 | 0.73 | CD274 (0.50) | S1PR4HPGDMAPTNPSR1TDP1 | |
| SCHEMBL13078669 | 0.73 | SLC9A1 (0.63) | S1PR4S1PR5MAPTNPSR1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009078588-A2 | COMPOSITION FOR PREVENTION AND TREATMENT OF CANCER CONTAINING PYRIMIDINE DERIVATIVES INHIBITING ACTIVITY OF PROTEIN PHOSPHATASES OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF AS AN ACTIVE INGREDIENT | KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY (KR) | 2009-06-25 | — | — | WO | disclosed |