Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 8/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.43 |
| ▸ | NPC1 | O15118 | 5/20 | 0.43 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | CASP3 | P42574 | 2/20 | 0.43 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.43 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13808613 | 0.82 | ALDH1A1 (0.45) | ALDH1A1MEN1KMT2ANPSR1RAB9A | |
| SCHEMBL21119020 | 0.79 | MAPT (0.56) | ALDH1A1MEN1KMT2ANPSR1RAB9A | |
| SCHEMBL13809597 | 0.79 | S1PR4 (0.52) | ALDH1A1MEN1KMT2ANPSR1SMN1; SMN2 | |
| SCHEMBL13809598 | 0.78 | NPFFR1 (0.44) | ALDH1A1MEN1KMT2ANPSR1RAB9A | |
| SCHEMBL12261863 | 0.78 | ALDH1A1 (0.44) | ALDH1A1MEN1KMT2ANPSR1RAB9A | |
| SCHEMBL9970934 | 0.77 | AMY1A (0.47) | ALDH1A1MEN1KMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL1616485 | 0.76 | ALDH1A1 (0.53) | ALDH1A1MEN1KMT2ANPSR1RAB9A | |
| SCHEMBL13718652 | 0.75 | MAPT (0.48) | ALDH1A1MEN1KMT2ANPSR1RAB9A | |
| SCHEMBL19237535 | 0.73 | S1PR4 (0.47) | ALDH1A1MEN1KMT2ANPSR1RAB9A | |
| SCHEMBL5543164 | 0.72 | ALDH1A1 (0.53) | ALDH1A1MEN1KMT2ANPSR1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120157306-A1 | Substituted Fused Pyrimidinones and Dihydropyrimidinones | BAYER CROPSCIENCE AG (DE) | 2012-06-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120157306-A1 | Substituted Fused Pyrimidinones and Dihydropyrimidinones | DHPS, FDPS, DPYD | ALDH1A1 333/4885MEN1 3414/4885KMT2A 3719/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.