Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 8/20 | 0.53 |
| ▸ | NPC1 | O15118 | 4/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 8/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | TP53 | P04637 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 5/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13810586 | 0.86 | RAB9A (0.66) | RAB9ANPC1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL4334222 | 0.86 | SMN1; SMN2 (0.48) | RAB9ACYP2D6CYP2C19MAPTSMN1; SMN2 | |
| SCHEMBL13810554 | 0.86 | PPARG (0.43) | RAB9ANPC1CYP2D6CYP2C19HTT | |
| SCHEMBL13810562 | 0.86 | PPARG (0.42) | RAB9ANPC1HTTMAPTSMN1; SMN2 | |
| SCHEMBL13810553 | 0.86 | PPARG (0.45) | RAB9ANPC1CYP2D6CYP2C19MAPT | |
| SCHEMBL13810572 | 0.85 | KMT2A (0.43) | CYP2D6CYP2C19MAPTSMN1; SMN2MEN1 | |
| SCHEMBL4331640 | 0.85 | PPARG (0.42) | RAB9ANPC1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL13810555 | 0.84 | PPARG (0.41) | RAB9ANPC1CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL4334617 | 0.83 | ALDH1A1 (0.41) | RAB9ANPC1CYP2D6CYP2C19HTT | |
| SCHEMBL4341131 | 0.83 | RAB9A (0.57) | RAB9ANPC1CYP1A2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7544835-B2 | Carboxylic acid derivative and salt thereof | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2009-06-09 | — | — | US | disclosed |
| US-7544835-B2 | Carboxylic acid derivative and salt thereof | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2009-06-09 | — | — | US | disclosed |