Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.67 |
| ▸ | THRB | P10828 | 1/20 | 0.64 |
| ▸ | WDR5 | P61964 | 2/20 | 0.63 |
| ▸ | FABP4 | P15090 | 2/20 | 0.61 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.61 |
| ▸ | POLB | P06746 | 2/20 | 0.59 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.59 |
| ▸ | USP2 | O75604 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | CASP3 | P42574 | 1/20 | 0.55 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.55 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.55 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.55 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9864676 | 0.88 | MAPT (0.53) | ALDH1A1THRBWDR5FABP4MEN1 | |
| SCHEMBL15888492 | 0.87 | ALDH1A1 (0.54) | ALDH1A1THRBWDR5POLBLMNA | |
| SCHEMBL27424129 | 0.86 | THRB (0.65) | ALDH1A1THRBWDR5FABP4FABP5 | |
| SCHEMBL31006706 | 0.86 | THRB (0.65) | ALDH1A1THRBWDR5FABP4FABP5 | |
| SCHEMBL4397021 | 0.84 | FABP4 (0.62) | ALDH1A1THRBWDR5FABP4FABP5 | |
| SCHEMBL7372681 | 0.84 | USP2 (0.69) | ALDH1A1THRBWDR5FABP4FABP5 | |
| SCHEMBL3718775 | 0.84 | TSHR (0.65) | ALDH1A1FABP4POLBMEN1KMT2A | |
| SCHEMBL17102998 | 0.82 | IDH1 (0.65) | MAPT | |
| SCHEMBL27424450 | 0.81 | HSD17B2 (0.70) | ALDH1A1THRBWDR5FABP4FABP5 | |
| SCHEMBL633994 | 0.81 | ALDH1A1 (0.68) | ALDH1A1MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7553809-B2 | Fc receptor modulators and uses thereof | ILEXUS PTY LIMITED (AU) | 2009-06-30 | — | — | US | disclosed |