Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX1 | P51575 | 11/20 | 0.60 |
| ▸ | P2RX4 | Q99571 | 3/20 | 0.60 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.60 |
| ▸ | TMPRSS4 | Q9NRS4 | 4/20 | 0.55 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.53 |
| ▸ | FADS1 | O60427 | 3/20 | 0.50 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | PARP1 | P09874 | 1/20 | 0.48 |
| ▸ | PLG | P00747 | 1/20 | 0.47 |
| ▸ | KLK1 | P06870 | 1/20 | 0.47 |
| ▸ | KLK6 | Q92876 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13812558 | 0.90 | P2RX1 (0.59) | P2RX1P2RX4P2RX7TMPRSS4SLC2A1 | |
| SCHEMBL13812570 | 0.88 | TMPRSS4 (0.69) | P2RX1P2RX4P2RX7TMPRSS4SLC2A1 | |
| SCHEMBL13812633 | 0.82 | P2RX1 (0.59) | P2RX1P2RX4P2RX7TMPRSS4SLC2A1 | |
| SCHEMBL13812580 | 0.81 | TMPRSS4 (0.69) | P2RX1P2RX4P2RX7TMPRSS4SLC2A1 | |
| SCHEMBL13812621 | 0.81 | P2RX1 (0.67) | P2RX1P2RX4P2RX7TMPRSS4SLC2A1 | |
| SCHEMBL13812554 | 0.79 | MEN1 (0.59) | P2RX1P2RX4P2RX7TMPRSS4SLC2A1 | |
| SCHEMBL3881082 | 0.78 | FADS1 (0.56) | P2RX1P2RX4P2RX7TMPRSS4SLC2A1 | |
| SCHEMBL11932152 | 0.77 | P2RX1 (1.00) | P2RX1P2RX4P2RX7TMPRSS4SLC2A1 | |
| SCHEMBL13812620 | 0.77 | FADS1 (0.65) | P2RX1P2RX4P2RX7TMPRSS4SLC2A1 | |
| SCHEMBL4272739 | 0.77 | P2RX1 (0.72) | P2RX1P2RX4P2RX7TMPRSS4SLC2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7547804-B2 | Compounds, compositions, and methods employing same | MYRIAD GENETICS, INC. (US) | 2009-06-16 | — | — | US | disclosed |
| US-7547804-B2 | Compounds, compositions, and methods employing same | MYRIAD GENETICS, INC. (US) | 2009-06-16 | — | — | US | disclosed |