Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.59 |
| ▸ | P2RX1 | P51575 | 5/20 | 0.56 |
| ▸ | P2RX4 | Q99571 | 2/20 | 0.56 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 5/20 | 0.53 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.53 |
| ▸ | INSR | P06213 | 1/20 | 0.53 |
| ▸ | IGF1R | P08069 | 1/20 | 0.53 |
| ▸ | SRC | P12931 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | TMPRSS4 | Q9NRS4 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13812634 | 0.83 | P2RX1 (0.55) | MEN1KMT2AP2RX1P2RX4P2RX7 | |
| SCHEMBL13189702 | 0.83 | NPC1 (0.70) | MEN1KMT2AP2RX1P2RX4P2RX7 | |
| SCHEMBL13812570 | 0.82 | TMPRSS4 (0.69) | MEN1KMT2AP2RX1P2RX4P2RX7 | |
| SCHEMBL13812580 | 0.80 | TMPRSS4 (0.69) | MEN1KMT2AP2RX1P2RX4P2RX7 | |
| SCHEMBL13812621 | 0.80 | P2RX1 (0.67) | P2RX1P2RX4P2RX7TMPRSS4SLC2A1 | |
| SCHEMBL13812556 | 0.79 | P2RX1 (0.60) | P2RX1P2RX4P2RX7SMN1; SMN2TMPRSS4 | |
| SCHEMBL13812558 | 0.78 | P2RX1 (0.59) | P2RX1P2RX4P2RX7SMN1; SMN2TMPRSS4 | |
| SCHEMBL13189708 | 0.76 | NPC1 (0.74) | MEN1KMT2AP2RX1P2RX4P2RX7 | |
| SCHEMBL3881082 | 0.75 | FADS1 (0.56) | MEN1KMT2AP2RX1P2RX4P2RX7 | |
| SCHEMBL11932152 | 0.74 | P2RX1 (1.00) | P2RX1P2RX4P2RX7TMPRSS4SLC2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7547804-B2 | Compounds, compositions, and methods employing same | MYRIAD GENETICS, INC. (US) | 2009-06-16 | — | — | US | disclosed |
| US-7547804-B2 | Compounds, compositions, and methods employing same | MYRIAD GENETICS, INC. (US) | 2009-06-16 | — | — | US | disclosed |