Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX1 | P51575 | 10/20 | 0.60 |
| ▸ | FADS1 | O60427 | 3/20 | 0.59 |
| ▸ | P2RX4 | Q99571 | 2/20 | 0.58 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.58 |
| ▸ | TMPRSS4 | Q9NRS4 | 4/20 | 0.56 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.51 |
| ▸ | SGMS2 | Q8NHU3 | 2/20 | 0.51 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.50 |
| ▸ | MET | P08581 | 1/20 | 0.49 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.48 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13812601 | 0.90 | P2RX1 (0.58) | P2RX1FADS1P2RX4P2RX7TMPRSS4 | |
| SCHEMBL13812651 | 0.85 | P2RX1 (0.62) | P2RX1FADS1P2RX4P2RX7TMPRSS4 | |
| SCHEMBL13189711 | 0.85 | P2RX1 (0.65) | P2RX1FADS1P2RX4P2RX7TMPRSS4 | |
| SCHEMBL13812610 | 0.84 | P2RX1 (0.61) | P2RX1FADS1P2RX4P2RX7TMPRSS4 | |
| SCHEMBL13812611 | 0.84 | P2RX1 (0.66) | P2RX1FADS1P2RX4P2RX7TMPRSS4 | |
| SCHEMBL13189709 | 0.83 | FADS1 (0.82) | P2RX1FADS1P2RX4P2RX7TMPRSS4 | |
| SCHEMBL13812595 | 0.83 | P2RX1 (0.60) | P2RX1FADS1P2RX4P2RX7TMPRSS4 | |
| SCHEMBL13812905 | 0.81 | KCNMA1 (0.57) | P2RX1TMPRSS4SGMS2 | |
| SCHEMBL11781796 | 0.81 | KMT2A (0.55) | SGMS2OPRL1 | |
| SCHEMBL13812633 | 0.80 | P2RX1 (0.59) | P2RX1FADS1P2RX4P2RX7TMPRSS4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7547804-B2 | Compounds, compositions, and methods employing same | MYRIAD GENETICS, INC. (US) | 2009-06-16 | — | — | US | disclosed |
| US-7547804-B2 | Compounds, compositions, and methods employing same | MYRIAD GENETICS, INC. (US) | 2009-06-16 | — | — | US | disclosed |