Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FADS1 | O60427 | 2/20 | 0.82 |
| ▸ | P2RX1 | P51575 | 12/20 | 0.69 |
| ▸ | P2RX4 | Q99571 | 3/20 | 0.67 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.67 |
| ▸ | TMPRSS4 | Q9NRS4 | 4/20 | 0.61 |
| ▸ | TP53 | P04637 | 2/20 | 0.60 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.59 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.59 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | KCNMA1 | Q12791 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | USP2 | O75604 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4270372 | 0.86 | FADS1 (0.81) | FADS1P2RX1P2RX4P2RX7TMPRSS4 | |
| SCHEMBL30771745 | 0.86 | FADS1 (0.81) | FADS1P2RX1P2RX4P2RX7TMPRSS4 | |
| SCHEMBL13812611 | 0.86 | P2RX1 (0.66) | FADS1P2RX1P2RX4P2RX7TMPRSS4 | |
| SCHEMBL13812651 | 0.85 | P2RX1 (0.62) | FADS1P2RX1P2RX4P2RX7TMPRSS4 | |
| SCHEMBL13189706 | 0.85 | P2RX1 (0.72) | FADS1P2RX1P2RX4P2RX7TMPRSS4 | |
| SCHEMBL13189711 | 0.85 | P2RX1 (0.65) | FADS1P2RX1P2RX4P2RX7TMPRSS4 | |
| SCHEMBL13812610 | 0.84 | P2RX1 (0.61) | FADS1P2RX1P2RX4P2RX7TMPRSS4 | |
| SCHEMBL13812595 | 0.83 | P2RX1 (0.60) | FADS1P2RX1P2RX4P2RX7TMPRSS4 | |
| SCHEMBL13812632 | 0.83 | P2RX1 (0.60) | FADS1P2RX1P2RX4P2RX7TMPRSS4 | |
| SCHEMBL13812585 | 0.83 | FADS1 (0.61) | FADS1P2RX1P2RX4P2RX7TMPRSS4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010101648-A1 | GLUTAMATE RECEPTOR MODULATORS AND THERAPEUTIC AGENTS | WOOD RICHARD D (US) | 2010-09-10 | — | — | WO | disclosed |