Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNMA1 | Q12791 | 7/20 | 0.52 |
| ▸ | TMPRSS4 | Q9NRS4 | 9/20 | 0.51 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | MRGPRX1 | Q96LB2 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | GRM5 | P41594 | 1/20 | 0.42 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.42 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.42 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13812629 | 0.94 | TMPRSS4 (0.55) | KCNMA1TMPRSS4TP53MAPTGAA | |
| SCHEMBL13812727 | 0.93 | TMPRSS4 (0.51) | KCNMA1TMPRSS4TP53MAPTRAB9A | |
| SCHEMBL13812685 | 0.90 | TMPRSS4 (0.65) | KCNMA1TMPRSS4MEN1KMT2AKDM4E | |
| SCHEMBL13812728 | 0.90 | TMPRSS4 (0.50) | KCNMA1TMPRSS4MAPTSMN1; SMN2GAA | |
| SCHEMBL13812687 | 0.89 | TMPRSS4 (0.50) | KCNMA1TMPRSS4TP53MAPTRAB9A | |
| SCHEMBL13812838 | 0.88 | TMPRSS4 (0.55) | KCNMA1TMPRSS4TP53MAPTGAA | |
| SCHEMBL13812691 | 0.87 | TMPRSS4 (0.48) | KCNMA1TMPRSS4MEN1KMT2AMRGPRX1 | |
| SCHEMBL13812682 | 0.87 | TMPRSS4 (0.50) | KCNMA1TMPRSS4TP53MAPTRAB9A | |
| SCHEMBL13812700 | 0.84 | KCNMA1 (0.58) | KCNMA1TMPRSS4TP53MAPTRAB9A | |
| SCHEMBL13812730 | 0.84 | TMPRSS4 (0.49) | KCNMA1TMPRSS4TP53MAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7547804-B2 | Compounds, compositions, and methods employing same | MYRIAD GENETICS, INC. (US) | 2009-06-16 | — | — | US | disclosed |
| US-7547804-B2 | Compounds, compositions, and methods employing same | MYRIAD GENETICS, INC. (US) | 2009-06-16 | — | — | US | disclosed |