Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMPRSS4 | Q9NRS4 | 14/20 | 0.49 |
| ▸ | P2RX1 | P51575 | 5/20 | 0.46 |
| ▸ | P2RX4 | Q99571 | 3/20 | 0.45 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.45 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | IKBKB | O14920 | 1/20 | 0.42 |
| ▸ | CHUK | O15111 | 1/20 | 0.42 |
| ▸ | KDR | P35968 | 1/20 | 0.42 |
| ▸ | FLT3 | P36888 | 1/20 | 0.42 |
| ▸ | MYLK | Q15746 | 1/20 | 0.42 |
| ▸ | MAP4K5 | Q9Y4K4 | 1/20 | 0.42 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.42 |
| ▸ | KCNMA1 | Q12791 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13812687 | 0.85 | TMPRSS4 (0.50) | TMPRSS4P2RX1P2RX4P2RX7SLC2A1 | |
| SCHEMBL13812822 | 0.84 | TMPRSS4 (0.50) | TMPRSS4P2RX1P2RX4P2RX7SLC2A1 | |
| SCHEMBL13812838 | 0.84 | TMPRSS4 (0.55) | TMPRSS4P2RX1P2RX4P2RX7SLC2A1 | |
| SCHEMBL13812629 | 0.84 | TMPRSS4 (0.55) | TMPRSS4P2RX1P2RX4P2RX7SLC2A1 | |
| SCHEMBL13812699 | 0.84 | MEN1 (0.50) | TMPRSS4P2RX1P2RX4P2RX7MEN1 | |
| SCHEMBL13812695 | 0.84 | KCNMA1 (0.52) | TMPRSS4P2RX1P2RX4P2RX7SLC2A1 | |
| SCHEMBL13812727 | 0.84 | TMPRSS4 (0.51) | TMPRSS4P2RX1P2RX4P2RX7SLC2A1 | |
| SCHEMBL13812689 | 0.83 | P2RX1 (0.63) | TMPRSS4P2RX1P2RX4P2RX7SLC2A1 | |
| SCHEMBL13812682 | 0.81 | TMPRSS4 (0.50) | TMPRSS4P2RX1P2RX4P2RX7SLC2A1 | |
| SCHEMBL13812685 | 0.81 | TMPRSS4 (0.65) | TMPRSS4P2RX1P2RX4P2RX7SLC2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7547804-B2 | Compounds, compositions, and methods employing same | MYRIAD GENETICS, INC. (US) | 2009-06-16 | — | — | US | disclosed |
| US-7547804-B2 | Compounds, compositions, and methods employing same | MYRIAD GENETICS, INC. (US) | 2009-06-16 | — | — | US | disclosed |