Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMPRSS4 | Q9NRS4 | 9/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | FADS1 | O60427 | 1/20 | 0.46 |
| ▸ | KCNMA1 | Q12791 | 3/20 | 0.45 |
| ▸ | P2RX1 | P51575 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13812629 | 0.92 | TMPRSS4 (0.55) | TMPRSS4GAAKCNMA1P2RX1KDM4E | |
| SCHEMBL13812695 | 0.90 | KCNMA1 (0.52) | TMPRSS4GAAKCNMA1P2RX1KDM4E | |
| SCHEMBL13812685 | 0.89 | TMPRSS4 (0.65) | TMPRSS4KCNMA1P2RX1KDM4EHPGD | |
| SCHEMBL13812838 | 0.86 | TMPRSS4 (0.55) | TMPRSS4GAAKCNMA1P2RX1KDM4E | |
| SCHEMBL13812691 | 0.85 | TMPRSS4 (0.48) | TMPRSS4KCNMA1P2RX1MEN1KMT2A | |
| SCHEMBL13812687 | 0.85 | TMPRSS4 (0.50) | TMPRSS4GAAKCNMA1P2RX1KDM4E | |
| SCHEMBL13812698 | 0.85 | KCNMA1 (0.51) | TMPRSS4GAAPPARGFADS1KCNMA1 | |
| SCHEMBL13812727 | 0.84 | TMPRSS4 (0.51) | TMPRSS4GAAKCNMA1P2RX1KDM4E | |
| SCHEMBL13812684 | 0.82 | KCNMA1 (0.59) | GAAKCNMA1P2RX1KDM4EMAPT | |
| SCHEMBL13812653 | 0.81 | KCNMA1 (0.55) | TMPRSS4GAAKCNMA1P2RX1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7547804-B2 | Compounds, compositions, and methods employing same | MYRIAD GENETICS, INC. (US) | 2009-06-16 | — | — | US | disclosed |
| US-7547804-B2 | Compounds, compositions, and methods employing same | MYRIAD GENETICS, INC. (US) | 2009-06-16 | — | — | US | disclosed |