Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMPRSS4 | Q9NRS4 | 10/20 | 0.68 |
| ▸ | P2RX1 | P51575 | 7/20 | 0.68 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | P2RX4 | Q99571 | 4/20 | 0.58 |
| ▸ | P2RX7 | Q99572 | 4/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | IKBKB | O14920 | 1/20 | 0.55 |
| ▸ | CHUK | O15111 | 1/20 | 0.55 |
| ▸ | KDR | P35968 | 1/20 | 0.55 |
| ▸ | FLT3 | P36888 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | MYLK | Q15746 | 1/20 | 0.55 |
| ▸ | MAP4K5 | Q9Y4K4 | 1/20 | 0.55 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.55 |
| ▸ | DDR1 | Q08345 | 2/20 | 0.52 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | CDK1 | P06493 | 1/20 | 0.49 |
| ▸ | TUBB | P07437 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30100387 | 0.87 | TMPRSS4 (0.67) | TMPRSS4P2RX1LMNAHPGDP2RX4 | |
| SCHEMBL23675370 | 0.87 | TMPRSS4 (0.67) | TMPRSS4P2RX1LMNAHPGDP2RX4 | |
| SCHEMBL18341428 | 0.84 | TMPRSS4 (0.81) | TMPRSS4P2RX1LMNAHPGDP2RX4 | |
| SCHEMBL13812674 | 0.81 | TMPRSS4 (1.00) | TMPRSS4P2RX1LMNAHPGDP2RX4 | |
| SCHEMBL13812668 | 0.81 | LMNA (0.80) | TMPRSS4P2RX1LMNAHPGDP2RX4 | |
| SCHEMBL30100395 | 0.79 | ERCC1 (0.59) | TMPRSS4P2RX1LMNAP2RX4P2RX7 | |
| SCHEMBL23675382 | 0.79 | ERCC1 (0.59) | TMPRSS4P2RX1LMNAP2RX4P2RX7 | |
| SCHEMBL330023 | 0.79 | TMPRSS4 (0.83) | TMPRSS4P2RX1P2RX4P2RX7MEN1 | |
| SCHEMBL13812877 | 0.78 | TMPRSS4 (0.68) | TMPRSS4P2RX1LMNAHPGDP2RX4 | |
| SCHEMBL13812881 | 0.78 | ACLY (0.54) | TMPRSS4P2RX1LMNAHPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7547804-B2 | Compounds, compositions, and methods employing same | MYRIAD GENETICS, INC. (US) | 2009-06-16 | — | — | US | disclosed |
| US-7547804-B2 | Compounds, compositions, and methods employing same | MYRIAD GENETICS, INC. (US) | 2009-06-16 | — | — | US | disclosed |