Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNK3 | O14649 | 6/20 | 0.47 |
| ▸ | KCNK9 | Q9NPC2 | 6/20 | 0.47 |
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | FADS1 | O60427 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | AHR | P35869 | 1/20 | 0.43 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13812803 | 0.94 | TRPV1 (0.50) | KCNK3KCNK9POLBKMT2AFADS1 | |
| SCHEMBL13812936 | 0.94 | FADS1 (0.49) | KCNK3KCNK9POLBKMT2AALDH1A1 | |
| SCHEMBL13812776 | 0.92 | KCNK3 (0.51) | KCNK3KCNK9POLBKMT2AALDH1A1 | |
| SCHEMBL13812948 | 0.92 | FADS1 (0.50) | KCNK3KCNK9POLBKMT2AFADS1 | |
| SCHEMBL13812809 | 0.92 | POLB (0.51) | KCNK3KCNK9POLBKMT2AFADS1 | |
| SCHEMBL13812942 | 0.91 | POLB (0.50) | KCNK3KCNK9POLBKMT2AMAPK1 | |
| SCHEMBL13812938 | 0.90 | GAA (0.47) | KCNK3KCNK9POLBKMT2AALDH1A1 | |
| SCHEMBL13812935 | 0.89 | FADS1 (0.47) | KCNK3KCNK9POLBKMT2AALDH1A1 | |
| SCHEMBL13812946 | 0.89 | FADS1 (0.54) | KCNK3KCNK9POLBKMT2AFADS1 | |
| SCHEMBL13812944 | 0.88 | KCNK3 (0.45) | KCNK3KCNK9POLBMAPK1FADS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7547804-B2 | Compounds, compositions, and methods employing same | MYRIAD GENETICS, INC. (US) | 2009-06-16 | — | — | US | disclosed |
| US-7547804-B2 | Compounds, compositions, and methods employing same | MYRIAD GENETICS, INC. (US) | 2009-06-16 | — | — | US | disclosed |