Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FADS1 | O60427 | 3/20 | 0.54 |
| ▸ | P2RX1 | P51575 | 3/20 | 0.48 |
| ▸ | GRM5 | P41594 | 1/20 | 0.48 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.47 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.44 |
| ▸ | AURKA | O14965 | 1/20 | 0.44 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.44 |
| ▸ | KCNK3 | O14649 | 2/20 | 0.43 |
| ▸ | KCNK9 | Q9NPC2 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13812948 | 0.94 | FADS1 (0.50) | FADS1P2RX1GRM5P2RX4P2RX7 | |
| SCHEMBL13812803 | 0.93 | TRPV1 (0.50) | FADS1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL13812809 | 0.92 | POLB (0.51) | FADS1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL13812935 | 0.91 | FADS1 (0.47) | FADS1P2RX1GRM5NPC1RAB9A | |
| SCHEMBL13812936 | 0.90 | FADS1 (0.49) | FADS1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL13812942 | 0.89 | POLB (0.50) | FADS1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL13812934 | 0.89 | KCNK3 (0.47) | FADS1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL13812947 | 0.89 | SIRT2 (0.47) | FADS1P2RX1P2RX4P2RX7NPC1 | |
| SCHEMBL13812938 | 0.88 | GAA (0.47) | FADS1P2RX1NPC1RAB9AMEN1 | |
| SCHEMBL13812944 | 0.88 | KCNK3 (0.45) | FADS1NPC1RAB9APOLBKCNK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7547804-B2 | Compounds, compositions, and methods employing same | MYRIAD GENETICS, INC. (US) | 2009-06-16 | — | — | US | disclosed |
| US-7547804-B2 | Compounds, compositions, and methods employing same | MYRIAD GENETICS, INC. (US) | 2009-06-16 | — | — | US | disclosed |