Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 5/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.45 |
| ▸ | KCNK3 | O14649 | 2/20 | 0.45 |
| ▸ | KCNK9 | Q9NPC2 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | STAT3 | P40763 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13812950 | 0.89 | RAB9A (0.58) | RAB9ANPC1KDM4EPOLBSIRT2 | |
| SCHEMBL13812954 | 0.86 | RAB9A (0.51) | RAB9ANPC1KDM4EPOLBSIRT2 | |
| SCHEMBL13812760 | 0.86 | LRRK2 (0.56) | LRRK2RAB9ANPC1KDM4EPOLB | |
| SCHEMBL13812742 | 0.85 | KCNK3 (0.56) | RAB9ANPC1KDM4EPOLBSIRT2 | |
| SCHEMBL13812747 | 0.83 | SMN1; SMN2 (0.52) | RAB9ANPC1KDM4EPOLBSIRT2 | |
| SCHEMBL13812739 | 0.83 | SMN1; SMN2 (0.52) | RAB9ANPC1KDM4EPOLBSIRT2 | |
| SCHEMBL13812774 | 0.82 | SIRT2 (0.57) | RAB9ANPC1KDM4EPOLBSIRT2 | |
| SCHEMBL13812765 | 0.82 | KCNK3 (0.55) | RAB9ANPC1KDM4EPOLBSIRT2 | |
| SCHEMBL13812952 | 0.81 | NPC1 (0.48) | RAB9ANPC1KDM4EPOLBSIRT2 | |
| SCHEMBL13812770 | 0.80 | KCNK3 (0.61) | RAB9ANPC1KDM4EPOLBSIRT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7547804-B2 | Compounds, compositions, and methods employing same | MYRIAD GENETICS, INC. (US) | 2009-06-16 | — | — | US | disclosed |
| US-7547804-B2 | Compounds, compositions, and methods employing same | MYRIAD GENETICS, INC. (US) | 2009-06-16 | — | — | US | disclosed |