Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | EGFR | P00533 | 5/20 | 0.50 |
| ▸ | ERBB2 | P04626 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | ALB | P02768 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6279910 | 0.83 | EGFR (0.56) | NPSR1EGFRERBB2ALDH1A1LMNA | |
| SCHEMBL13800951 | 0.81 | EGFR (0.51) | NPSR1EGFRERBB2ALDH1A1USP2 | |
| SCHEMBL8634991 | 0.80 | EGFR (0.56) | NPSR1EGFRERBB2ALDH1A1LMNA | |
| SCHEMBL5931139 | 0.80 | ALDH1A1 (0.71) | NPSR1EGFRERBB2ALDH1A1LMNA | |
| SCHEMBL29165183 | 0.79 | ALDH1A1 (0.59) | NPSR1EGFRERBB2ALDH1A1LMNA | |
| SCHEMBL13800952 | 0.78 | MAPT (0.70) | EGFRERBB2ALDH1A1USP2TDP1 | |
| SCHEMBL8545310 | 0.75 | EGFR (0.60) | NPSR1EGFRERBB2ALDH1A1LMNA | |
| SCHEMBL7969578 | 0.75 | EGFR (0.60) | NPSR1EGFRERBB2ALDH1A1LMNA | |
| SCHEMBL28405273 | 0.75 | EGFR (0.60) | NPSR1EGFRERBB2ALDH1A1LMNA | |
| SCHEMBL9178660 | 0.74 | ALDH1A1 (0.61) | EGFRERBB2ALDH1A1LMNAALB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090163697-A1 | Multicomponent coupling and glycopeptide synthesis with cyclic thioanhydrides | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS | 2009-06-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090163697-A1 | Multicomponent coupling and glycopeptide synthesis with cyclic thioanhydrides | LNPEP, CLSPN, GALNT14 | NPSR1 981/4885EGFR 3361/4885ERBB2 2653/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.