Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | SPTLC2 | O15270 | 5/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | CNR1 | P21554 | 2/20 | 0.42 |
| ▸ | CNR2 | P34972 | 2/20 | 0.42 |
| ▸ | STS | P08842 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.42 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.41 |
| ▸ | HTR3B | O95264 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.41 |
| ▸ | HTR3A | P46098 | 1/20 | 0.41 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13801612 | 1.00 | KMT2A (0.43) | KMT2AUSP30HDAC4HDAC6SPTLC2 | |
| SCHEMBL13801611 | 0.94 | HTR3E (0.44) | KMT2AUSP30HDAC4HDAC6SPTLC2 | |
| SCHEMBL13814603 | 0.94 | HTR3E (0.44) | KMT2AUSP30HDAC4HDAC6SPTLC2 | |
| SCHEMBL13814678 | 0.93 | TACR2 (0.45) | KMT2AUSP30HDAC4HDAC6SPTLC2 | |
| SCHEMBL13801614 | 0.93 | TACR2 (0.45) | KMT2AUSP30HDAC4HDAC6SPTLC2 | |
| SCHEMBL13801636 | 0.93 | TACR2 (0.45) | KMT2AUSP30HDAC4HDAC6SPTLC2 | |
| SCHEMBL13801256 | 0.93 | TACR2 (0.45) | KMT2AUSP30HDAC4HDAC6SPTLC2 | |
| SCHEMBL13814586 | 0.93 | TACR2 (0.45) | KMT2AUSP30HDAC4HDAC6SPTLC2 | |
| SCHEMBL13801288 | 0.90 | TACR3 (0.48) | KMT2AUSP30HDAC4HDAC6SPTLC2 | |
| SCHEMBL13814659 | 0.90 | TACR3 (0.48) | KMT2AUSP30HDAC4HDAC6SPTLC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090156572-A1 | Nitrogen-containing heterocyclic compound and use thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED | 2009-06-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090156572-A1 | Nitrogen-containing heterocyclic compound and use thereof | NTSR2, NTSR1, HNMT | KMT2A 977/4885USP30 3991/4885HDAC4 1035/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.