Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.61 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 4/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6539272 | 0.83 | LMNA (0.54) | MAPTGAALMNAL3MBTL1SMN1; SMN2 | |
| SCHEMBL25758742 | 0.82 | ALDH1A1 (0.62) | MAPTGAALMNAL3MBTL1SMN1; SMN2 | |
| SCHEMBL13823115 | 0.82 | MAPT (0.67) | MAPTGAAL3MBTL1SMN1; SMN2ALDH1A1 | |
| SCHEMBL8248742 | 0.81 | SMN1; SMN2 (0.64) | GAALMNAL3MBTL1SMN1; SMN2ALDH1A1 | |
| SCHEMBL8241785 | 0.81 | RAB9A (0.66) | MAPTGAALMNAL3MBTL1SMN1; SMN2 | |
| SCHEMBL23605758 | 0.80 | MAPT (0.69) | MAPTGAALMNAL3MBTL1SMN1; SMN2 | |
| SCHEMBL10765557 | 0.80 | SMN1; SMN2 (0.63) | MAPTLMNAL3MBTL1SMN1; SMN2ALDH1A1 | |
| SCHEMBL6538992 | 0.79 | GAA (0.61) | MAPTGAALMNAL3MBTL1SMN1; SMN2 | |
| SCHEMBL20024729 | 0.79 | MAPT (0.57) | MAPTGAALMNAL3MBTL1SMN1; SMN2 | |
| SCHEMBL24806561 | 0.79 | MAPT (0.67) | MAPTGAALMNASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7541454-B2 | Compounds and methods for fluorescent labeling | EPOCH BIOSCIENCES, INC. (US) | 2009-06-02 | — | — | US | disclosed |