Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.40 |
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | RECQL | P46063 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.33 |
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22962412 | 0.81 | MAPT (0.39) | MAPTKDM4EPOLBALDH1A1HPGD | |
| SCHEMBL20375410 | 0.81 | MAPT (0.39) | MAPTKDM4EPOLBALDH1A1HPGD | |
| SCHEMBL14646337 | 0.81 | MAPT (0.39) | MAPTKDM4EPOLBALDH1A1HPGD | |
| SCHEMBL24916459 | 0.78 | IDO1 (0.38) | MAPTNPSR1RAB9ASMN1; SMN2GAA | |
| SCHEMBL19142380 | 0.78 | MAPT (0.37) | MAPTNPSR1RAB9ASMN1; SMN2GAA | |
| SCHEMBL24023526 | 0.77 | GAA (0.31) | MAPTKDM4EALDH1A1HPGDRAB9A | |
| SCHEMBL2495661 | 0.77 | POLB (0.46) | MAPTKDM4EPOLBALDH1A1HPGD | |
| SCHEMBL21204295 | 0.76 | MAPT (0.44) | MAPTKDM4EPOLBALDH1A1HPGD | |
| SCHEMBL25456261 | 0.74 | LMNA (0.38) | MAPTKDM4EALDH1A1HPGDRAB9A | |
| SCHEMBL874034 | 0.73 | TDP1 (0.55) | MAPTKDM4EPOLBALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200231563-A1 | NOVEL HETEROCYCLIC COMPOUNDS AS MODULATORS OF MGLUR7 | PRAGMA THERAPEUTICS (FR) | 2020-07-23 | — | — | US | disclosed |
| US-10705274-B2 | Optically anisotropic layer and production method therefor, optically anisotropic laminate and production method therefor, optically anisotropic transfer body, polarization plate, and image display device | ZEON COPORATION (JP) | 2020-07-07 | — | — | US | disclosed |
| US-20190113667-A1 | OPTICALLY ANISOTROPIC LAYER AND PRODUCTION METHOD THEREFOR, OPTICALLY ANISOTROPIC LAMINATE AND PRODUCTION METHOD THEREFOR, OPTICALLY ANISOTROPIC TRANSFER BODY, POLARIZATION PLATE, AND IMAGE DISPLAY DEVICE | ZEON CORPORATION (JP) | 2019-04-18 | — | — | US | disclosed |
| US-8431695-B2 | Pyrrolo[2,1-f][1,2,4]triazin-4-ylamines IGF-1R kinase inhibitors for the treatment of cancer and other hyperproliferative diseases | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2013-04-30 | — | — | US | disclosed |
| EP-2067778-A1 | Quinoxaline derivative, and light emitting element, licht emitting device and electronic appliance using the same | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) | 2009-06-10 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200231563-A1 | NOVEL HETEROCYCLIC COMPOUNDS AS MODULATORS OF MGLUR7 | GRM7, GRM1, GRM3 | MAPT 1190/4885KDM4E 1947/4885POLB 4548/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.