Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH2 | P25021 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 8/20 | 0.37 |
| ▸ | DRD3 | P35462 | 7/20 | 0.37 |
| ▸ | HTR1A | P08908 | 6/20 | 0.37 |
| ▸ | DRD4 | P21917 | 4/20 | 0.37 |
| ▸ | HTR2B | P41595 | 4/20 | 0.37 |
| ▸ | HTR2A | P28223 | 4/20 | 0.36 |
| ▸ | HTR2C | P28335 | 3/20 | 0.36 |
| ▸ | DRD1 | P21728 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | KDM2B | Q8NHM5 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13806201 | 0.90 | HRH2 (0.40) | HRH2HRH1DRD2DRD3HTR1A | |
| Hydrochloric Acid SCHEMBL4253181 | 0.89 | HRH2 (0.39) | HRH2HRH1DRD2DRD3HTR1A | |
| SCHEMBL13806147 | 0.78 | HTR1A (0.41) | HRH2HRH1DRD2HTR1ADRD4 | |
| SCHEMBL4257010 | 0.78 | OPRD1 (0.43) | DRD2KDM2BHPGDSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL4258032 | 0.77 | HTR1A (0.40) | HRH2HRH1DRD2HTR1ADRD4 | |
| Hydrochloric Acid SCHEMBL4257008 | 0.77 | OPRD1 (0.43) | DRD2KDM2BHPGDSMN1; SMN2 | |
| SCHEMBL4252096 | 0.76 | HRH2 (0.44) | HRH2HRH1DRD2DRD3HTR1A | |
| Hydrochloric Acid SCHEMBL4257966 | 0.76 | HRH2 (0.43) | HRH2HRH1DRD2HTR1ADRD4 | |
| SCHEMBL4252945 | 0.74 | MAPT (0.37) | HRH2HRH1HTR1AGAAHPGD | |
| SCHEMBL13816771 | 0.72 | KDM4E (0.41) | HPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090156589-A1 | 1,2-DI(CYCLIC GROUP)SUBSTITUTED BENZENE DERIVATIVE | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2009-06-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090156589-A1 | 1,2-DI(CYCLIC GROUP)SUBSTITUTED BENZENE DERIVATIVE | CCR10, H1-10, VCAM1 | HRH2 65/4885HRH1 64/4885DRD2 746/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.