Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.30 |
| ▸ | PPARD | Q03181 | 1/20 | 0.30 |
| ▸ | PPARA | Q07869 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13808401 | 0.76 | L3MBTL1 (0.39) | TP53PPARGPPARDPPARA | |
| SCHEMBL13808393 | 0.73 | CYP1A2 (0.34) | PPARGPPARDPPARA | |
| SCHEMBL18079355 | 0.72 | L3MBTL1 (0.37) | PPARGPPARDPPARA | |
| SCHEMBL18079125 | 0.72 | L3MBTL1 (0.37) | PPARGPPARDPPARA | |
| SCHEMBL20353942 | 0.69 | SLC2A1 (0.41) | TP53 | |
| SCHEMBL19887929 | 0.68 | L3MBTL1 (0.34) | — | |
| SCHEMBL19887960 | 0.68 | L3MBTL1 (0.34) | — | |
| SCHEMBL13882350 | 0.68 | HCRTR1 (0.37) | — | |
| SCHEMBL19891908 | 0.68 | L3MBTL1 (0.33) | PPARGPPARDPPARA | |
| SCHEMBL19891956 | 0.68 | L3MBTL1 (0.33) | PPARGPPARDPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7544400-B2 | Bimesogenic compounds and flexoelectric devices | MERCK PATENT GMBH (DE) | 2009-06-09 | — | — | US | disclosed |
| US-20080142758-A1 | Bimesogenic Compounds And Flexoelectric Devices | MERCK PATENT GMBH (DE) | 2008-06-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080142758-A1 | Bimesogenic Compounds And Flexoelectric Devices | MLX, FOXM1, SFXN1 | TP53 3681/4885PPARG 4297/4885PPARD 4491/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.