Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSA | P10619 | 10/20 | 0.45 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13817540 | 0.89 | NPC1 (0.39) | CTSANPC1RAB9AFFAR1MRGPRX4 | |
| SCHEMBL4484469 | 0.84 | CNR2 (0.35) | CTSANPC1RAB9AFFAR1MRGPRX4 | |
| SCHEMBL4506759 | 0.84 | FFAR1 (0.43) | CTSANPC1RAB9AFFAR1 | |
| SCHEMBL4501790 | 0.82 | L3MBTL1 (0.47) | CTSAIDO1NPC1RAB9AFFAR1 | |
| SCHEMBL4492426 | 0.82 | FFAR1 (0.39) | CTSAIDO1NPC1RAB9AFFAR1 | |
| SCHEMBL13817539 | 0.82 | NR3C2 (0.39) | CTSANPC1RAB9AFFAR1 | |
| SCHEMBL4499232 | 0.81 | ALOX5 (0.38) | CTSANPC1RAB9AFFAR1 | |
| SCHEMBL4486697 | 0.81 | NPC1 (0.33) | CTSANPC1RAB9A | |
| SCHEMBL13817538 | 0.80 | FFAR1 (0.37) | CTSANPC1RAB9AFFAR1MRGPRX4 | |
| SCHEMBL4483012 | 0.80 | MAOB (0.40) | CTSAIDO1NPC1RAB9AFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7541472-B2 | 3-Aryl-3-hydroxy-2-methylenepropionic acid esters as fungicides | CROPSOLUTION, INC. (US) | 2009-06-02 | — | — | US | disclosed |
| US-7541472-B2 | 3-Aryl-3-hydroxy-2-methylenepropionic acid esters as fungicides | CROPSOLUTION, INC. (US) | 2009-06-02 | — | — | US | disclosed |