Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | CTSA | P10619 | 4/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.38 |
| ▸ | MRGPRX4 | Q96LA9 | 9/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13817537 | 0.89 | CTSA (0.45) | NPC1RAB9ACTSAFFAR1MRGPRX4 | |
| SCHEMBL4484469 | 0.87 | CNR2 (0.35) | NPC1RAB9ACTSAFFAR1MRGPRX4 | |
| SCHEMBL4495946 | 0.83 | CASP1 (0.44) | CTSAMAPT | |
| SCHEMBL4506759 | 0.83 | FFAR1 (0.43) | NPC1RAB9ACTSAFFAR1MAPT | |
| SCHEMBL13817470 | 0.82 | IDO1 (0.42) | CTSAFFAR1CNR2 | |
| SCHEMBL4501790 | 0.82 | L3MBTL1 (0.47) | NPC1RAB9ACTSAFFAR1FFAR4 | |
| SCHEMBL4492426 | 0.81 | FFAR1 (0.39) | NPC1RAB9ACTSAFFAR1MRGPRX4 | |
| SCHEMBL13817481 | 0.80 | P2RX7 (0.39) | NPC1RAB9ACTSAFFAR4 | |
| SCHEMBL4499435 | 0.79 | FFAR1 (0.39) | NPC1RAB9AFFAR1MRGPRX4CNR2 | |
| SCHEMBL4483012 | 0.79 | MAOB (0.40) | NPC1RAB9ACTSAFFAR1FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7541472-B2 | 3-Aryl-3-hydroxy-2-methylenepropionic acid esters as fungicides | CROPSOLUTION, INC. (US) | 2009-06-02 | — | — | US | disclosed |
| US-7541472-B2 | 3-Aryl-3-hydroxy-2-methylenepropionic acid esters as fungicides | CROPSOLUTION, INC. (US) | 2009-06-02 | — | — | US | disclosed |