SCHEMBL13817618

SCHEMBL13817618

BrC(Br)=NNc1ccccc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 6/20 0.44
MAPT P10636 6/20 0.44
KDM4E B2RXH2 2/20 0.44
NPSR1 Q6W5P4 2/20 0.44
TDP1 Q9NUW8 3/20 0.43
TSHR P16473 2/20 0.43
CYP1A1 P04798 1/20 0.43
CYP1B1 Q16678 1/20 0.43
MEN1 O00255 5/20 0.42
KMT2A Q03164 5/20 0.42
ALDH1A1 P00352 5/20 0.42
RAB9A P51151 4/20 0.42
LMNA P02545 2/20 0.42
IDO1 P14902 1/20 0.42
NOX1 Q9Y5S8 1/20 0.41
NPC1 O15118 2/20 0.41
CASP3 P42574 1/20 0.41
SENP8 Q96LD8 1/20 0.41
SENP7 Q9BQF6 1/20 0.41
SENP6 Q9GZR1 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15519815 0.76 MAPT (0.41) GAAMAPTNPSR1TDP1MEN1
SCHEMBL15939608 0.76 ALDH1A1 (0.49) GAAMAPTKDM4ETDP1MEN1
SCHEMBL2746282 0.75 GAA (0.53) GAAMAPTKDM4ENPSR1TDP1
SCHEMBL3086579 0.75 GAA (0.50) GAAMAPTKDM4ENPSR1TDP1
SCHEMBL8977349 0.75 GAA (0.46) GAAMAPTKDM4ENPSR1MEN1
SCHEMBL8977354 0.75 GAA (0.46) GAAMAPTKDM4ENPSR1MEN1
SCHEMBL934433 0.73 GAA (0.61) GAAMAPTKDM4ENPSR1TDP1
SCHEMBL13664153 0.73 MAPT (0.51) GAAMAPTNPSR1MEN1KMT2A
SCHEMBL4164253 0.73 MAPT (0.47) GAAMAPTKDM4ETDP1MEN1
SCHEMBL11783078 0.72 GFER (0.40) GAAMAPTKDM4ENPSR1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7541377-B2 Substituted anthranilamides for controlling invertebrate pests E.I. DU PONT DE NEMOURS AND COMPANY (US) 2009-06-02 US disclosed
US-20070203201-A1 Substituted anthranilamides for controlling invertebrate pests FINKELSTEIN BRUCE L 2007-08-30 US disclosed
US-7199138-B2 Substituted anthranilamides for controlling invertebrate pests E. I. DU PONT DE NEMOURS AND COMPANY (US) 2007-04-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070203201-A1 Substituted anthranilamides for controlling invertebrate pests ANTXR2, PRXL2A, F9 GAA 2042/4885MAPT 4845/4885KDM4E 794/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.