Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 3/20 | 0.40 |
| ▸ | PITRM1 | Q5JRX3 | 3/20 | 0.40 |
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.40 |
| ▸ | DPP9 | Q86TI2 | 3/20 | 0.40 |
| ▸ | DPP7 | Q9UHL4 | 3/20 | 0.40 |
| ▸ | FAP | Q12884 | 2/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | XIAP | P98170 | 1/20 | 0.32 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.32 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.32 |
| ▸ | NR1I2 | O75469 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8239464 | 0.90 | DPP4 (0.42) | DPP4PITRM1DPP8DPP9DPP7 | |
| SCHEMBL8246062 | 0.89 | DPP4 (0.41) | DPP4PITRM1DPP8DPP9DPP7 | |
| SCHEMBL8240611 | 0.87 | DPP4 (0.38) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL8246145 | 0.87 | DPP4 (0.42) | DPP4PITRM1DPP8DPP9DPP7 | |
| SCHEMBL8281869 | 0.86 | DPP4 (0.42) | DPP4PITRM1DPP8DPP9DPP7 | |
| SCHEMBL12600611 | 0.85 | DPP4 (0.38) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL14595892 | 0.84 | CTSV (0.38) | — | |
| SCHEMBL13817720 | 0.84 | CTSV (0.38) | — | |
| SCHEMBL8280783 | 0.84 | CTSV (0.38) | — | |
| SCHEMBL14279155 | 0.84 | DPP4 (0.32) | DPP4PITRM1DPP8DPP9DPP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1737881-B1 | NOVEL COMPOUNDS AS INHIBITORS OF HEPATITIS C VIRUS NS3 SERINE PROTEASE | SCHERING CORP (US) | 2009-06-24 | — | — | EP | disclosed |