Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29843671 | 0.81 | LMNA (0.32) | — | |
| SCHEMBL3161115 | 0.80 | — | — | |
| SCHEMBL11974296 | 0.76 | CTSK (0.32) | — | |
| SCHEMBL3160837 | 0.76 | — | — | |
| SCHEMBL13226301 | 0.69 | LMNA (0.33) | — | |
| SCHEMBL27527940 | 0.69 | GRIN2B (0.34) | — | |
| SCHEMBL15537624 | 0.68 | MEN1 (0.33) | — | |
| SCHEMBL3164034 | 0.68 | FFAR3 (0.30) | — | |
| SCHEMBL19164297 | 0.67 | CTSL (0.32) | — | |
| SCHEMBL15536547 | 0.66 | FFAR3 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7553841-B2 | Amino cyclobutylamide modulators of chemokine receptor activity | MERCK & CO., INC. (US) | 2009-06-30 | — | — | US | disclosed |
| US-7553841-B2 | Amino cyclobutylamide modulators of chemokine receptor activity | MERCK & CO., INC. (US) | 2009-06-30 | — | — | US | disclosed |