Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | GFER | P55789 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.47 |
| ▸ | DRD4 | P21917 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.47 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13181438 | 0.92 | ALDH1A1 (0.64) | ALDH1A1KMT2AGFERL3MBTL1CYP2D6 | |
| SCHEMBL13181454 | 0.91 | ALDH1A1 (0.61) | ALDH1A1KMT2AGFERKDM4EL3MBTL1 | |
| SCHEMBL7387492 | 0.84 | DRD4 (0.47) | KDM4EL3MBTL1CYP2J2DRD4HRH2 | |
| SCHEMBL13181422 | 0.81 | THRA (0.49) | ALDH1A1KMT2AGFERL3MBTL1THRB | |
| SCHEMBL5476524 | 0.81 | SMYD2 (0.62) | ALDH1A1KMT2AGFERKDM4EL3MBTL1 | |
| SCHEMBL13362469 | 0.80 | DRD4 (0.46) | KDM4EDRD4THRBHRH2HRH1 | |
| SCHEMBL10603564 | 0.80 | ALDH1A1 (0.81) | ALDH1A1KMT2AGFERKDM4EL3MBTL1 | |
| SCHEMBL7645836 | 0.80 | ALDH1A1 (0.81) | ALDH1A1KMT2AGFERKDM4EL3MBTL1 | |
| SCHEMBL13181456 | 0.79 | ALDH1A1 (0.66) | ALDH1A1KMT2AL3MBTL1SMN1; SMN2LMNA | |
| Hydrochloric Acid SCHEMBL10606849 | 0.79 | ALDH1A1 (0.82) | ALDH1A1KMT2AGFERKDM4EL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2070909-A1 | Non-steroidal progesterone receptor modulators | Bayer Schering Pharma AG (DE) | 2009-06-17 | — | — | EP | disclosed |