Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 3/20 | 0.52 |
| ▸ | CES1 | P23141 | 3/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 2/20 | 0.48 |
| ▸ | CA2 | P00918 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | GSK3B | P49841 | 2/20 | 0.45 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | MAOA | P21397 | 2/20 | 0.44 |
| ▸ | MAOB | P27338 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5781080 | 0.94 | MAP4K4 (0.50) | CES2CES1ALOX15TSHRLMNA | |
| SCHEMBL9864000 | 0.89 | PARP10 (0.52) | ALDH1A1MAPTRAB9AMAOAMAOB | |
| SCHEMBL1450228 | 0.88 | PARP10 (0.39) | TSHRLMNAL3MBTL1ALDH1A1MAPT | |
| SCHEMBL11699267 | 0.82 | ALDH1A1 (0.42) | CES2CES1ALOX15TSHRLMNA | |
| SCHEMBL2081411 | 0.80 | CES2 (0.52) | CES2CES1ALOX15TSHRLMNA | |
| SCHEMBL126170 | 0.79 | ALOX15 (0.58) | CES2CES1ALOX15TSHRLMNA | |
| SCHEMBL11798461 | 0.79 | PARP10 (0.47) | ALOX15TSHRLMNAKDM4EALDH1A1 | |
| SCHEMBL6203654 | 0.79 | CES2 (0.68) | CES2CES1ALOX15TSHRLMNA | |
| SCHEMBL10552849 | 0.79 | CES2 (0.54) | CES2CES1ALOX15TSHRLMNA | |
| SCHEMBL1033882 | 0.79 | TSHR (0.57) | CES2CES1ALOX15TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3921317-A1 | 3-AMINO-2-[2-(ACYLAMINO)PYRIDIN-4-YL]-1,5,6,7-TETRAHYDRO-4H-PYRROLO[3,2-C]PYRIDIN-4-ONE AS CSNK1 INHIBITORS | Bayer Aktiengesellschaft (DE) | 2021-12-15 | — | — | EP | claimed |
| WO-2020161257-A1 | 3-AMINO-2-[2-(ACYLAMINO)PYRIDIN-4-YL]-1,5,6,7-TETRAHYDRO-4H-PYRROLO[3,2-C]PYRIDIN-4-ONE AS CSNK1 INHIBITORS | BAYER AKTIENGESELLSCHAFT (DE) | 2020-08-13 | — | — | WO | claimed |
| CN-110124735-A | A kind of hydrophilic electroconductive hydrogel cathode catalysis film and its preparation method and application | 中钢集团鞍山热能研究院有限公司 | 2019-08-16 | — | — | CN | claimed |
| JP-4828407-B2 | — | — | 2011-11-30 | — | — | JP | claimed |
| EP-1594869-A2 | 3-SUBSTITUTED-2(ARYLALKYL)-1-AZABICYCLOALKANES AND METHODS OF USE THEREOF | Targacept, Inc. (US) | 2005-11-16 | — | — | EP | claimed |
| WO-2004076449-A2 | 3-SUBSTITUTED-2(ARYLALKYL)-1-AZABICYCLOALKANES AND METHODS OF USE THEREOF | TARGACEPT, INC. (US) | 2004-09-10 | — | — | WO | claimed |
| CN-118955381-A | Pyrazole compound as well as preparation method and application thereof | 赣南师范大学 | 2024-11-15 | — | — | CN | disclosed |
| CN-117219278-A | Schizophrenia aggressive behavior risk assessment model and application thereof | 福建省立医院 | 2023-12-12 | — | — | CN | disclosed |
| CN-117191993-A | Metabolic biomarker for aggressive behavior of schizophrenia and screening method thereof | 郑富豪 | 2023-12-08 | — | — | CN | disclosed |
| CN-110124735-A | A kind of hydrophilic electroconductive hydrogel cathode catalysis film and its preparation method and application | 中钢集团鞍山热能研究院有限公司 | 2019-08-16 | — | — | CN | disclosed |
| US-20160272600-A1 | INHIBITORS OF BETA-SECRETASE | VITAE PHARMACEUTICALS, LLC | 2016-09-22 | — | — | US | disclosed |
| US-20070042275-A1 | Composition for optical recording, optical recording medium, and production method thereof | FUJI PHOTO FILM CO., LTD. | 2007-02-22 | — | — | US | disclosed |
| US-4302484-A | Polymers crosslinkable by electron beams | BAYER AKTIENGESELLSCHAFT (DE) | 1981-11-24 | — | — | US | disclosed |
| EP-0001997-B1 | ELECTRON BEAM-CURABLE PHOTORESIST LACQUERS | BAYER AG (DE) | 1981-02-11 | — | — | EP | disclosed |
| EP-0001997-A1 | Electron beam-curable photoresist lacquers | BAYER AG (DE) | 1979-05-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160272600-A1 | INHIBITORS OF BETA-SECRETASE | BACE1, BACE2, PSEN1 | CES2 943/4885CES1 361/4885ALOX15 2821/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.