Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 7/20 | 0.72 |
| ▸ | CYP1A2 | P05177 | 7/20 | 0.72 |
| ▸ | CACNA1C | Q13936 | 6/20 | 0.72 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.72 |
| ▸ | MAPT | P10636 | 6/20 | 0.72 |
| ▸ | CYP2C9 | P11712 | 6/20 | 0.72 |
| ▸ | CYP2C19 | P33261 | 6/20 | 0.72 |
| ▸ | TSHR | P16473 | 4/20 | 0.72 |
| ▸ | NFKB1 | P19838 | 4/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.72 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.72 |
| ▸ | LMNA | P02545 | 3/20 | 0.72 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.72 |
| ▸ | ABCC4 | O15439 | 2/20 | 0.72 |
| ▸ | CACNA1F | O60840 | 2/20 | 0.72 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.72 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.72 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.72 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.72 |
| ▸ | SCN1A | P35498 | 2/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12314043 | 0.88 | ADORA3 (0.75) | ADORA3CYP1A2CACNA1CCYP3A4MAPT | |
| SCHEMBL6859870 | 0.88 | CACNA1D (0.71) | ADORA3CYP1A2CACNA1CCYP3A4MAPT | |
| SCHEMBL18062192 | 0.85 | CACNA1D (0.51) | ADORA3CYP1A2CACNA1CCYP3A4MAPT | |
| Nifedipine SCHEMBL1172946 | 0.84 | ADORA3 (1.00) | ADORA3CYP1A2CACNA1CCYP3A4MAPT | |
| Nifedipine SCHEMBL29349595 | 0.84 | ADORA3 (1.00) | ADORA3CYP1A2CACNA1CCYP3A4MAPT | |
| Nifedipine SCHEMBL3968 | 0.84 | ADORA3 (1.00) | ADORA3CYP1A2CACNA1CCYP3A4MAPT | |
| Nifedipine SCHEMBL3858071 | 0.83 | ADORA3 (0.97) | ADORA3CYP1A2CACNA1CCYP3A4MAPT | |
| Nifedipine SCHEMBL8851402 | 0.83 | ADORA3 (0.97) | ADORA3CYP1A2CACNA1CCYP3A4MAPT | |
| Nifedipine SCHEMBL8851397 | 0.83 | ADORA3 (0.97) | ADORA3CYP1A2CACNA1CCYP3A4MAPT | |
| Nifedipine SCHEMBL5694031 | 0.83 | ADORA3 (0.97) | ADORA3CYP1A2CACNA1CCYP3A4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9709710-B2 | Device including light blocking layer and method of patterning the light blocking layer | SAMSUNG SDI CO., LTD. (KR) | 2017-07-18 | — | — | US | disclosed |
| US-20160259095-A1 | Device Including Light Blocking Layer and Method of Patterning the Light Blocking Layer | SAMSUNG SDI CO., LTD. (KR) | 2016-09-08 | — | — | US | disclosed |
| US-20150024054-A1 | SOLID PHARMACEUTICAL DISPERSIONS WITH ENHANCED BIOAVAILABILITY | BEND RESEARCH, INC. (US) | 2015-01-22 | — | — | US | disclosed |
| US-20130224301-A1 | SOLID PHARMACEUTICAL DISPERSIONS WITH ENHANCED BIOAVAILABILITY | BEND RESEARCH, INC. (US) | 2013-08-29 | — | — | US | disclosed |
| US-8431159-B2 | Solid pharmaceutical dispersions with enhanced bioavailability | BEND RESEARCH, INC. (US) | 2013-04-30 | — | — | US | disclosed |
| US-8367118-B2 | Solid pharmaceutical dispersions with enhanced bioavailability | BEND RESEARCH, INC. (US) | 2013-02-05 | — | — | US | disclosed |
| US-20120328679-A1 | SOLID PHARMACEUTICAL DISPERSIONS WITH ENHANCED BIOAVAILABILITY | BEND RESEARCH, INC. | 2012-12-27 | — | — | US | disclosed |
| US-8337899-B2 | Solid pharmaceutical dispersions with enhanced bioavailability | BEND RESEARCH, INC. (US) | 2012-12-25 | — | — | US | disclosed |
| US-20120292797-A1 | SOLID PHARMACEUTICAL DISPERSIONS WITH ENHANCED BIOAVAILABILITY | BEND RESEARCH, INC. | 2012-11-22 | — | — | US | disclosed |
| US-20120289571-A1 | POLYMERIC CONJUGATES OF AROMATIC AMINE CONTAINING COMPOUNDS INCLUDING RELEASABLE UREA LINKER | ENZON PHARMACEUTICALS, INC. (US) | 2012-11-15 | — | — | US | disclosed |
| US-20120288542-A1 | SOLID PHARMACEUTICAL DISPERSIONS WITH ENHANCED BIOAVAILABILITY | BEND RESEARCH, INC. | 2012-11-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120328679-A1 | SOLID PHARMACEUTICAL DISPERSIONS WITH ENHANCED BIOAVAILABILITY | SUCNR1, SUCLA2, SI | ADORA3 2796/4885CYP1A2 145/4885CACNA1C 1806/4885 |
| US-20120288542-A1 | SOLID PHARMACEUTICAL DISPERSIONS WITH ENHANCED BIOAVAILABILITY | SBDS, SUCNR1, SI | ADORA3 2103/4885CYP1A2 162/4885CACNA1C 1719/4885 |
| US-20130224301-A1 | SOLID PHARMACEUTICAL DISPERSIONS WITH ENHANCED BIOAVAILABILITY | SUCNR1, SUCLA2, SI | ADORA3 2796/4885CYP1A2 145/4885CACNA1C 1806/4885 |
| US-20150024054-A1 | SOLID PHARMACEUTICAL DISPERSIONS WITH ENHANCED BIOAVAILABILITY | SUCNR1, SUCLA2, SI | ADORA3 2796/4885CYP1A2 145/4885CACNA1C 1806/4885 |
| US-20120289571-A1 | POLYMERIC CONJUGATES OF AROMATIC AMINE CONTAINING COMPOUNDS INCLUDING RELEASABLE UREA LINKER | AURKA, DSTYK, TYR | ADORA3 853/4885CYP1A2 3424/4885CACNA1C 4867/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.