Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | RGS12 | O14924 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | JMJD6 | Q6NYC1 | 2/20 | 0.32 |
| ▸ | FPR2 | P25090 | 2/20 | 0.31 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.31 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.31 |
| ▸ | ELANE | P08246 | 1/20 | 0.31 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | OGA | O60502 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30554029 | 0.76 | ALDH1A1 (0.40) | ALDH1A1KDM4EHPGDHSD17B10RGS12 | |
| SCHEMBL10216908 | 0.76 | KMT2A (0.41) | ALDH1A1KDM4EHPGDLMNAMAPT | |
| SCHEMBL12706154 | 0.75 | LPO (0.42) | ALDH1A1KDM4EHPGDHSD17B10RGS12 | |
| SCHEMBL30554007 | 0.75 | HPGD (0.38) | ALDH1A1KDM4EHPGDHSD17B10RGS12 | |
| SCHEMBL10217046 | 0.74 | MAPK1 (0.39) | ALDH1A1HSD17B10LMNAMAPT | |
| SCHEMBL30554028 | 0.73 | JMJD6 (0.42) | ALDH1A1KDM4EHPGDHSD17B10RGS12 | |
| SCHEMBL10217022 | 0.72 | KCNH2 (0.35) | ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL28413706 | 0.72 | ALDH1A1 (0.40) | ALDH1A1KDM4EHPGDHSD17B10RGS12 | |
| SCHEMBL4675474 | 0.72 | ALDH1A1 (0.40) | ALDH1A1KDM4EHPGDHSD17B10RGS12 | |
| SCHEMBL13031578 | 0.72 | ALDH1A1 (0.40) | ALDH1A1KDM4EHPGDHSD17B10RGS12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120289501-A1 | Benzene-fused 6-membered oxygen-containing heterocyclic derivatives of bicyclic heteroaryls | NOVARTIS AG (CH) | 2012-11-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120289501-A1 | Benzene-fused 6-membered oxygen-containing heterocyclic derivatives of bicyclic heteroaryls | CYP1B1, CYP11B2, CCNI | OPRD1 1615/4885ALDH1A1 385/4885KDM4E 1662/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.