Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.48 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.42 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.41 |
| ▸ | IMPDH2 | P12268 | 2/20 | 0.40 |
| ▸ | PRKCI | P41743 | 1/20 | 0.40 |
| ▸ | KIF11 | P52732 | 1/20 | 0.40 |
| ▸ | CHEK1 | O14757 | 3/20 | 0.39 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.38 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.38 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.37 |
| ▸ | GCGR | P47871 | 1/20 | 0.37 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.37 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.37 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | CDK1 | P06493 | 1/20 | 0.36 |
| ▸ | CDK4 | P11802 | 1/20 | 0.36 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.36 |
| ▸ | CCND1 | P24385 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24662784 | 0.92 | NOTUM (0.58) | NOTUMMKNK1PIK3CAIMPDH2PRKCI | |
| SCHEMBL13820313 | 0.92 | NOTUM (0.52) | NOTUMMKNK1PIK3CAIMPDH2MAPK14 | |
| SCHEMBL22956090 | 0.90 | NOTUM (0.56) | NOTUMMKNK1PIK3CAIMPDH2PRKCI | |
| SCHEMBL13820532 | 0.90 | CYP11B1 (0.43) | NOTUMMKNK1PIK3CACHEK1HSD17B1 | |
| SCHEMBL13820569 | 0.89 | KDM4E (0.42) | NOTUMMKNK1PIK3CAIMPDH2HSD17B1 | |
| SCHEMBL10030090 | 0.88 | NOTUM (0.52) | NOTUMMKNK1PIK3CAIMPDH2PRKCI | |
| SCHEMBL13820711 | 0.88 | HSD17B1 (0.44) | NOTUMMKNK1PIK3CAIMPDH2CHEK1 | |
| SCHEMBL13820610 | 0.88 | HSD17B1 (0.44) | NOTUMMKNK1PIK3CAIMPDH2CHEK1 | |
| SCHEMBL18810931 | 0.88 | NOTUM (0.56) | NOTUMMKNK1PIK3CAIMPDH2PRKCI | |
| SCHEMBL13820552 | 0.87 | KMT2A (0.42) | NOTUMMKNK1PIK3CAIMPDH2CHEK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120286251-A1 | NOVEL COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME | SAMSUNG DISPLAY CO., LTD. (KR) | 2012-11-15 | — | — | US | disclosed |
| US-20120286251-A1 | NOVEL COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME | SAMSUNG DISPLAY CO., LTD. (KR) | 2012-11-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120286251-A1 | NOVEL COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME | CRY1, LEF1, OR51E2 | NOTUM 1081/4885MKNK1 3616/4885PIK3CA 4631/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.