Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 19/20 | 0.51 |
| ▸ | DPP4 | P27487 | 1/20 | 0.44 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.44 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7005072 | 0.89 | ELANE (0.53) | ELANE | |
| SCHEMBL13299879 | 0.84 | ELANE (0.52) | ELANE | |
| SCHEMBL13822216 | 0.82 | ELANE (0.55) | ELANE | |
| SCHEMBL13822260 | 0.78 | ELANE (0.44) | ELANEDPP4DPP8DPP7 | |
| SCHEMBL7007704 | 0.78 | ELANE (0.55) | ELANE | |
| SCHEMBL13814746 | 0.77 | ELANE (0.50) | ELANE | |
| SCHEMBL13299881 | 0.75 | ELANE (0.46) | ELANEDPP4DPP8DPP7 | |
| SCHEMBL13299870 | 0.75 | ELANE (0.47) | ELANE | |
| SCHEMBL13299882 | 0.75 | ELANE (0.47) | ELANE | |
| SCHEMBL13299852 | 0.74 | ELANE (0.43) | ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090156509-A1 | Tri-peptide Inhibitors of Serine Elastases | ACCUTHERA, INC. (US) | 2009-06-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090156509-A1 | Tri-peptide Inhibitors of Serine Elastases | SCTR, CTRC, SERPINB1 | ELANE 4/4885DPP4 304/4885DPP8 438/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.