Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPBWR1 | P48145 | 1/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.33 |
| ▸ | TDO2 | P48775 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 3/20 | 0.32 |
| ▸ | RAB9A | P51151 | 3/20 | 0.32 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 3/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20390723 | 0.88 | ALDH1A1 (0.33) | ALDH1A1KMT2AMEN1KDM4EGAA | |
| SCHEMBL20390658 | 0.87 | KCNH2 (0.34) | ALDH1A1KMT2AMEN1KCNH2NPC1 | |
| SCHEMBL13659782 | 0.83 | LMNA (0.34) | ALDH1A1KMT2AMEN1LMNAKCNH2 | |
| SCHEMBL13659777 | 0.83 | KCNH2 (0.32) | ALDH1A1KMT2AMEN1KCNH2NPC1 | |
| SCHEMBL44771 | 0.82 | ALDH1A1 (0.49) | ALDH1A1KMT2AMEN1KDM4EGAA | |
| SCHEMBL13659785 | 0.81 | POLB (0.39) | ALDH1A1KMT2AMEN1GAALMNA | |
| SCHEMBL20390374 | 0.81 | KCNH2 (0.31) | KCNH2 | |
| SCHEMBL13122745 | 0.80 | NOTUM (0.37) | KCNH2 | |
| SCHEMBL13822146 | 0.75 | NOS3 (0.41) | ALDH1A1KMT2AMEN1GAAKCNH2 | |
| SCHEMBL13659737 | 0.75 | NOTUM (0.51) | ALDH1A1KMT2AMEN1KDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009075923-A2 | 6, 11-BRIDGED BIARYL MACROLIDES | ENANTA PHARMACEUTICALS, INC. (US) | 2009-06-18 | — | — | WO | disclosed |