SCHEMBL13822293

SCHEMBL13822293

C=CCOC(=O)Oc1nc(-c2ccc(Cl)c(OC)c2F)cc(N)c1Cl

nearest known ligand 0.35

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
MEP1B Q16820 1/20 0.34
AGPAT2 O15120 1/20 0.33
PKM P14618 1/20 0.33
PDCD1LG2 Q9BQ51 5/20 0.32
CD274 Q9NZQ7 5/20 0.32
ALDH1A1 P00352 1/20 0.31
TSHR P16473 1/20 0.31
HSD17B10 Q99714 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2465727 0.88 MEP1B (0.34) MEP1BPDCD1LG2CD274ALDH1A1TSHR
SCHEMBL2468807 0.86 MEP1B (0.36) MEP1BPDCD1LG2CD274ALDH1A1HSD17B10
SCHEMBL678977 0.85 ALDH1A1 (0.36) MEP1BAGPAT2PKMALDH1A1TSHR
SCHEMBL2596706 0.85 MEP1B (0.34) MEP1BPKM
SCHEMBL13822296 0.84 SCN10A (0.33) MEP1BPDCD1LG2CD274ALDH1A1HSD17B10
SCHEMBL2467541 0.82 ALDH1A1 (0.37) MEP1BPDCD1LG2CD274ALDH1A1TSHR
SCHEMBL2467740 0.82 SMN1; SMN2 (0.34) MEP1BPDCD1LG2CD274ALDH1A1
SCHEMBL2596708 0.82 ALOX5AP (0.33) MEP1BPDCD1LG2CD274ALDH1A1HSD17B10
SCHEMBL2596680 0.81 PDCD1LG2 (0.32) MEP1BPDCD1LG2CD274
SCHEMBL694302 0.80 MEP1B (0.32) MEP1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2514314-B1 Synergistic herbicidal composition containing certain pyridine carboxylic acids and certain cereal and rice herbicides DOW AGROSCIENCES LLC (US) 2016-06-15 EP claimed
EP-2524602-A1 Herbicide agent for tolerant or resistant soya cultures Bayer CropScience AG (DE) 2012-11-21 EP claimed
EP-2524602-A1 Herbicide agent for tolerant or resistant soya cultures Bayer CropScience AG (DE) 2012-11-21 EP disclosed